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Tazarotene



Tazarotene
Systematic (IUPAC) name
ethyl 6-[2-(4,4-dimethylthiochroman-6-yl) ethynyl] pyridine-3-carboxylate
Identifiers
CAS number 118292-40-3
ATC code D05AX05
PubChem 5381
DrugBank APRD01246
Chemical data
Formula C21H21NO2S 
Mol. mass 351.463 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding >99%
Metabolism  ?
Half life 19 Hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

X (U.S.)

Legal status

Prescription Only

Routes Topical

Tazarotene (marketed as Tazorac®, Avage® and Zorac®) is a prescription topical retinoid sold as a cream or gel. This medication is approved for treatment of psoriasis, acne, and sun damaged skin (photodamage). It is commonly sold in two concentrations: 0.05% and 0.1%.

Additional recommended knowledge

Common side effects include worsening of acne, dry skin, itchiness, redness and in some cases extreme drying and cracking of skin. For most patients these side effects are uncomfortable but mild and decrease markedly after the first 2–4 weeks of use.

For best results dermatologists recommend applying the cream or gel once daily before bedtime after washing the face with a mild soap.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tazarotene". A list of authors is available in Wikipedia.
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