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Tibotec is a pharmaceutical company with a focus on research and development for the treatment of infectious diseases such as HIV (AIDS), and Hepatitis C. The company develops antiretroviral drugs for the treatment of AIDS.



In 1994, Rudi Pauwels (Rega Institute for Medical Research) founded Tibotec, together with his wife Carine Claeys, and their first co-workers Marie-Pierre de Béthune, Kurt Hertogs, and Hilde Azijn. In 1995 Paul Stoffels (Janssen Pharmaceutica) joins Tibotec. The company was acquired by Johnson & Johnson in April 2002. The name of the company is derived from the tetrahydro-imidazo[4,5,1-jk][1,4]-benzodiazepine-2(1H)-one and -thione (TIBO) compounds discovered at the Rega Institute for Medical Research (Belgium)[1].


Tibotec licensed TMC120, a NNRTI, to the International Partnership for Microbicides for its development as a vaginal microbicide in March 2004.


  1. ^ Pauwels R, Andries K, Desmyter J, Schols D, Kukla MJ, Breslin HJ, Raeymaeckers A, Van Gelder J, Woestenborghs R, Heykants J, et al., Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives, Nature, 1990, 343, 470-474. doi:10.1038/343470a0

See also

William C. Weldon, Chairman & CEO

Past CEOs and presidents: Robert Wood Johnson I • James Wood Johnson • Robert Wood Johnson II • Robert Wood Johnson III • Philip B. Hofmann • Richard B. Sellars • James E. Burke • Ralph S. Larsen

Selected subsidiaries

ALZA CorporationCentocorCilagDePuy, Inc.Ethicon Endo-Surgery, Inc.Ethicon, Inc.Independence Technology, LLC • J&J PRDJanssen PharmaceuticaLifeScan • McNeil Consumer & Specialty Pharmaceuticals • Ortho-McNeil Pharmaceutical • Ortho-Neutrogena • Penaten • Tibotec

Major brands

Acuvue • Aveeno • Band-Aid • Carefree • Clean & Clear • Johnson's Baby • K-Y • Neutrogena • OneTouch • Rembrandt • Stayfree • Tylenol

Annual revenue: $53.3 billion USD 5.6% Annual income: $11.1 billion USD 9.9% (FY 2006) · Employees: 116,200 ·
Stock symbol: NYSE: JNJ · Website:   This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tibotec". A list of authors is available in Wikipedia.
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