Intermediates

Companies Intermediates

Enzymicals AG, Germany

Since its founding in 2009, Enzymicals AG has created a customer-oriented industrial platform for the process development and piloting of chemo-biocatalytic synthetic routs for high-quality fine chemicals and has built a bridge between academic research and industrial application. The focus of Enzy more

LANXESS Deutschland GmbH, Germany

LANXESS is a leading specialty chemicals company and operates in all important markets of the world. Its core business comprises the development, manufacture and sale of high-tech plastics, high-performance rubber, specialty chemicals and intermediates. In addition, it helps its customers in the dev more

BLD Pharmatech Inc., China

Found in 2014, BLDpharm, Inc. is a leading supplier and manufacturer of research chemicals to pharmaceutical companies, universities, biotech companies, healthcare industries, contract research organizations etc. With its own R&D center in Shanghai, BLDpharm main field of expertise covers the devel more

Products Intermediates

Look up Industrial Syntheses of 2,600 APIs

One-stop source of information relating to the industrial synthesis and commercial applications of every licensed drug of significance more

News Intermediates

• Development of an Efficient Enantioselective Desymmetrization Strategy Using Recombinant Pig Liver Esterases
  

  An economically significant process intensification for the efficient enzymatic synthesis of (1S,2R)-1-(methoxycarbonyl) cyclohex-4-ene-2-carboxylic acid was achieved by a careful adaption of the reaction mode to minimize mass transfer limitations. (1S,2R)-1-(methoxycarbonyl) cyclohex-4-ene-2-carbox more

• A new way to create molecules for drug development
  

  Chemists at The Ohio State University have developed a new and improved way to generate molecules that can enable the design of new types of synthetic drugs. Researchers say this new method of forming reactive intermediates called ketyl radicals offers scientists a way to use catalysts to convert si more

• Clariant breaks ground on joint venture production site in China
  

  Clariant and Beijing Tiangang Auxiliary Co., Ltd. (Tiangang), conducted a groundbreaking ceremony in Cangzhou (China), just over 200 km south of Beijing. The ceremony marked the start of the construction of a world-class production facility for stabilizers for plastics and textiles that will form th more

White papers Intermediates

• Glycerol in biodiesel and biodiesel blends
  

  The presented ion chromatographic method is applicable to all biodiesel types and blends. Before chromatographic separation, free glycerol and bound glycerol are isolated by a straightforward extraction and saponification-extraction technique. Pulsed more

Publications Intermediates

• Molecules, Vol. 23, Pages 1582: Triorganoindium Reagents in Rh-Catalyzed C–H Activation/C–C Cross-Coupling Reactions of 2-Arylpyridines

  Molecules, Vol. 23, Pages 1582: Triorganoindium Reagents in Rh-Catalyzed C–H Activation/C–C Cross-Coupling Reactions of 2-Arylpyridines Molecules doi: 10.3390/molecules23071582 Authors: Ricardo Riveiros Rubén Tato José Pérez Sestelo Luis A. Sarandeses The activation of C&nda more

• Conformational control and DNA-binding mechanism of the metazoan origin recognition complex [Biochemistry]

  The onset of chromosomal DNA replication relies on dedicated initiator proteins to chaperone ring-shaped helicases onto DNA. In most eukaryotes, initiators are multisubunit protein complexes that require ATP to bind DNA and to aid helicase recruitment and loading. Although structural studies have re more

• Roles of Gag-RNA interactions in HIV-1 virus assembly deciphered by single-molecule localization microscopy [Cell Biology]

  Single-molecule localization microscopy (SMLM) is useful for deciphering dynamic organizations of structures densely labeled by specific proteins in the cellular context with nanoscopic resolution not attainable by conventional imaging tools. Here we employed SMLM to investigate the mechanism by whi more