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77 Current news about the topic active pharmaceutical ingredients

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On our way to the bio-economy: High-performance biocatalyst discovered

Future applications primarily in the production of active pharmaceutical ingredients, but also in the synthesis of fine chemicals expected

22-May-2020

In the bioeconomy, biotechnological processes are replacing processes that rely on fossil resources. Microorganisms and enzymes are being used in targeted fashion as biocatalysts for industrial production. Researchers at the University of Bayreuth have now discovered an enzyme that offers great ...

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Catalysts combination opens doors to making useful compounds

17-Aug-2018

Researchers have developed a new method that aids in the process of making valuable compounds by using a unique combination of catalysts. Huimin Zhao, Professor of Chemical and Biomolecular Engineering and leader of the Biosystems Design research theme at the Carl R. Woese Institute for Genomic ...

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How to brew high-value fatty acids with brewer's yeast

15-Mar-2017

Short-chain fatty acids are high-value constituents of cosmetics, active pharmaceutical ingredients, antimicrobial substances, aromas or soap. To date, it has only been possible to extract them from crude oil by chemical means or from certain plants, such as coconut, using a complex process. ...

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Cool combination produces easier carbon bonds

25-Apr-2016

By combining two century-old techniques in organic chemistry, Syuzanna Harutyunyan is able to make organic compounds with greater ease and precision. Such compounds are important for drug discovery and development. Almost 90 percent of known active pharmaceutical ingredients contain one or more ...

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AMRI to Close Holywell, U.K. API Manufacturing Facility

08-Apr-2015

AMRI announced that it has decided to close its Holywell, U.K. facility following a consultation process with employee representatives. The Holywell site provides chemical development services and small- and large scale-manufacturing services of active pharmaceutical ingredients (API) and ...

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An assembly line for medications

Efavirenz can now be produced more cost efficiently and sustainable utilizing continuous flow chemistry.

25-Feb-2015

Researchers at the Max Planck Institute of Colloids and Interfaces (MPICI) and the Freie Universität Berlin have succeeded in developing better methods of producing APIs (active pharmaceutical ingredients). As a result, Efavirenz, one of the preferred agents for treating HIV in combination ...

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A question of style

The reaction rate of many molecules depends on their shape

08-Oct-2013

Most molecules occur in several shapes, which may behave very differently. Using a sorting machine for molecules, a German–Swiss research team can now for the first time directly measure the various reaction rates of different forms of the same compound. Many chemical compounds have numerous ...

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Ionic liquids could aid in the delivery of active pharmaceutical compounds in the body

23-Jan-2013

US scientists have provided a strategy to improve the properties of active pharmaceutical ingredients (APIs) by combining ionic liquids (used to improve the properties of solid APIs) with prodrugs (used to improve solubility, permeability and bioavailability of APIs). The prodrug ionic liquids ...

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Evocatal and RohnerChem announce strategic partnership for enzymatic chemistry development and upscaling

06-Feb-2012

Evocatal and RohnerChem combine their complementary services to offer customers a seamless solution for the development of high-performance biocatalytic processesand their rapid application in the synthesis of fine chemicals and API. The focus of this strategic partnership is to offer highly ...

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BASF increases prices for pharmaceutical excipients and active ingredients

31-Aug-2011

Effective September 1, 2011, BASF will increase the sales prices globally for all pharmaceutical excipients and generic active pharmaceutical ingredients by 10%. This price increase affects the entire excipients portfolio including all binders, disintegrants, coatings, solubilizers, and solvents. ...

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