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Innovation is based on creativity and research. The world wide web now offers unique possibilities for the rapid exchange of ideas and knowledge. Communication and dissemination of information in the area of chemistry and related disciplines are at the centre of the Beilstein-Instituts support activities. The Beilstein-Institut fulfils its mission through its own long-term projects and by supporting individuals and institutions committed to advancing science throughout the world. The Beilstein Open Access journals in organic chemistry and nanotechnology are a resource that is freely available to all scientists worldwide. International symposia are organized where scientists from different disciplines can meet to exchange their knowledge. In research and education innovative projects are supported by the Beilstein-Institut either directly or through professorships and stipends.
Elsevier Acquires the Beilstein Database
Elsevier announced the acquisition through its subsidiary MDL Information Systems GmbH, of the Beilstein Database, the world's largest compilation of chemical facts and the premier database in the field of organic chemistry. Elsevier has been exclusively involved in both the production an ... more
Nucleophilic fluoroalkylation/cyclization route to fluorinated phthalides
Abstract Discribed in this article is a versatile and practical method for the synthesis of C3-perfluoroalkyl-substituted phthalides in a one-pot manner. Upon treatment of KF or triethylamine, 2-cyanobenzaldehyde reacted with (perfluoroalkyl)trimethylsilanes via nucleophilic addition and ... more
Progress in copper-catalyzed trifluoromethylation
Abstract The introduction of trifluoromethyl groups into organic molecules has attracted great attention in the past five years. In this review, we describe the recent efforts in the development of trifluoromethylation via copper catalysis using nucleophilic, electrophilic or radical trif ... more
Abstract Herein, we demonstrate an improved short-step protocol for the synthesis of multicyclic molecules having a CF2CF2-containing cyclohexadiene or cyclohexane framework in a mesogenic structure. These molecules are promising candidates for vertical alignment (VA)-mode liquid crystal ... more
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