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Thieme Chemistry – Highly evaluated information in Synthetic Organic Chemistry
Thieme publishes highly evaluated information about synthetic and general chemistry for professional chemists and advanced students since 1909. Thieme Chemistry is part of the privately owned Thieme Publishing Group. We sell a full range of products: Journals, Reference Works, Encyclopedias and Monographs.
Look up Industrial Syntheses of 2,600 APIs
One-stop source of information relating to the industrial synthesis and commercial applications of every licensed drug of significance more
Synthesis Problems? Find Fast and Better Solutions for Organic Transformations
This tool for full-text reviews of organic transformations and experimental procedures helps improve your strategy for the design of new molecules more
Synthesis Problems? Find Fast and Better Solutions for Organic Transformations
Science of Synthesis is your one-stop tool for full-text reviews of organic transformations and experimental procedures. The online reference work helps speed up your literature research and improve your strategy for the design of new molecules. Science of Synthesis provides a critical revi ... more
Room-Temperature, Water-Promoted, Radical-Coupling Reactions of Phenols with tert-Butyl Nitrite
SynlettDOI: 10.1055/s-0036-1589038 A radical–radical cross-coupling reaction of phenols with tert-butyl nitrite has been developed with the use of water as an additive. This method allows the construction of C–N bonds under an air atmosphere at room temperature, providing the ortho-nitrate ... more
Direct ortho Arylation of Anisoles via the Formation of Four-Membered Lithiumcycles/Palladacycles
SynlettDOI: 10.1055/s-0036-1588863 We report here our latest discovery on the directed lithiation and palladium-catalyzed arylation of anisoles. During this research, the formation of a four-membered lithiumcycle followed by transmetalation to the corresponding palladacycle has been achiev ... more
Metal-free Oxidative Cross-Coupling Reaction of Aromatic Compounds Containing Heteroatoms
SynlettDOI: 10.1055/s-0036-1588455 The biaryl unit containing a heteroatom is a key structure in a large number of natural products and π-conjugated organic systems. The cross-couplings can provide powerful methods for the construction of biaryls and heterobiaryls; thus the development of ... more
