My watch list  


Systematic (IUPAC) name
heptane-2-carboxylic acid
CAS number 4697-36-3
ATC code J01CA03
PubChem 20824
DrugBank APRD00846
Chemical data
Formula C17H18N2O6S 
Mol. mass 378.401 g/mol
Pharmacokinetic data
Bioavailability 30 to 40%
Protein binding 30 to 60%
Metabolism Minimal
Half life 1 hour
Excretion Renal (30 to 40%)
Therapeutic considerations
Pregnancy cat.

B(US) Passes into breast milk

Legal status


Routes Oral

Carbenicillin is an antibiotic belonging to the carboxypenicillin subgroup of the penicillins. It has gram-negative coverage which includes Pseudomonas aeruginosa but limited gram-positive coverage. The carboxypenicillins are susceptible to degradation by beta-lactamase enzymes.

The antibiotic is very soluble in water and is acid-labile. Aqueous solutions are short-lived. Working concentration in the lab: up to 100 µg per ml.

It is a semi-synthetic analogue of the naturally occurring penicillin. Although much more expensive than ampicillin, it is much more stable.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Carbenicillin". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE