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Tazobactam



Tazobactam
Systematic (IUPAC) name
(2S,3S,5R)-3-methyl-4,4,7-trioxo-3-

(triazol-1-ylmethyl)-4$l^{6}-thia-1-azabicyclo[3.2.0] heptane-2-carboxylic acid

Identifiers
CAS number 89786-04-9
ATC code J01CG02
PubChem  ?
DrugBank EXPT03012
Chemical data
Formula C10H12N4O5S 
Mol. mass 300.289 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Tazobactam is a compound which inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin® or Zosyn®. It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.

Additional recommended knowledge

Tazobactam sodium is a derivative of the penicillin nucleus and is a penicillanic acid sulfone.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tazobactam". A list of authors is available in Wikipedia.
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