My watch list
my.chemeurope.com  
Login  

Cloxacillin



Cloxacillin
Systematic (IUPAC) name
(2S,5R,6R)-6-{[3-(2-chlorophenyl)-5-methyl-
oxazole-4-carbonyl]amino}-3,3-dimethyl-7-oxo-
4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
Identifiers
CAS number 61-72-3
ATC code J01CF02
PubChem 6098
DrugBank APRD00882
Chemical data
Formula C19H18ClN3O5S 
Mol. mass 435.882 g/mol
Pharmacokinetic data
Bioavailability 37 to 90%
Protein binding 95%
Metabolism  ?
Half life 30 minutes to 1 hour
Excretion Renal and biliary
Therapeutic considerations
Pregnancy cat.

B(US)

Legal status
Routes Oral, IM

Cloxacillin is a semisynthetic antibiotic in the same class as penicillin. It is sold under a number of trade names, including Cloxapen and Orbenin. Cloxacillin is used against staphylococci that produce beta-lactamase.

Additional recommended knowledge

This drug has a weaker antibacterial activity than benzylpencillin, and is devoid of serious toxicity except for allergic reactions.

See also

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cloxacillin". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE