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Ethotoin (marketed as Peganone® by Ovation) is an anticonvulsant drug used in the treatment of epilepsy. It is a hydantoin, similar to phenytoin. Ethotoin lacks phenytoin's side effects of gingival hyperplasia and hirsutism, however it is less effective. This, combined with the need for frequent dosing has limited its usefulness. Ethotoin is no longer widely used.
Additional recommended knowledge
Mechanism of action
Similar to phenytoin.
Indications and usage
Ethotoin is indicated for tonic-clonic and partial complex seizures.
Ethotoin is available in 250mg tablets. It is taken orally in 4 to 6 divided doses per day, preferably after food.
Ataxia, visual disturbances, rash and gastrointestinal problems.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ethotoin". A list of authors is available in Wikipedia.|