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Metharbital



Metharbital
Systematic (IUPAC) name
5,5-diethyl-1-methyl-hexahydropyrimidine-2,4,6-trione
Identifiers
CAS number 50-11-3
ATC code N03AA30
PubChem 4099
DrugBank APRD00757
Chemical data
Formula C9H14N2O3 
Mol. mass 198.219 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Metharbital was patented in 1905 by Emil Fischer working for Merck[1]. It was marketed as Gemonil by Abbott Laboratories. It is a barbiturate anticonvulsant, used in the treatment of epilepsy. It has similar properties to phenobarbital.

Additional recommended knowledge

History

  • 1952 Gemonil was introduced by Abbott Laboratories.
  • 1990 Abbott stopped marketing.

References

  • The Treatment of Epilepsy 2nd Ed by S. D. Shorvon (Editor), David R. Fish (Editor), Emilio Perucca (Editor), W. Edwin Dodson (Editor). Published by Blackwell 2004. ISBN 0-632-06046-8
  • The Medical Treatment of Epilepsy by Stanley R Resor. Published by Marcel Dekker (1991). ISBN 0-8247-8549-5.
  • The Comparative Toxicogenomics Database: Metharbital
  1. ^ US Patent 782742


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Metharbital". A list of authors is available in Wikipedia.
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