My watch list  


Systematic (IUPAC) name
CAS number 3258-51-3
ATC code  ?
PubChem 71122
Chemical data
Formula C10H14N2O4 
Mol. mass 226.229 g/mol
Synonyms Valofan, Valofane
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes  ?

Valofane is a sedative drug structurally related to the barbiturates[1] and similar drugs such as primidone. It is metabolised once inside the body to form the barbiturate proxibarbal and is thus a prodrug.[2]


  1. ^ Traversa U, Puppini P, Jacquot C, Vertua R. Effect of an atypical barbiturate, the 2-allophanyl-2-allyl-4-valerolactone (valofan), on exploratory behaviour and brain serotonin concentrations in mice. Journal de Pharmacologie. 1985 Jul-Sep;16(3):279-90.
  2. ^ Lambrey B, Compagnon PL, Jacquot C. Pharmacokinetics of 14C-2-allophanyl-2-allyl -gamma-valero-lactone: a prodrug of proxibarbal in rats. European Journal of Drug Metabolism and Pharmacokinetics. 1981;6(3):161-9.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Valofane". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE