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Gallamine



Gallamine
Systematic (IUPAC) name
N-[2-[2,3-bis (2-diethylaminoethoxy) phenoxy]ethyl]- N-ethyl-ethanamine
Identifiers
CAS number 65-29-2
ATC code M03AC02
PubChem 67425
DrugBank APRD00712
Chemical data
Formula C24H45N3O3
C30H60N3O3+3 · 3 I- (gallamine triethiodide)
Mol. mass 423.633 g/mol
891.529 g/mol (triethiodide)
Pharmacokinetic data
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Therapeutic considerations
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Legal status
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Gallamine (as gallamine triethiodide) is a non-depolarising muscle relaxant. It acts by combining with the cholinergic receptor sites in muscle and competitively blocking the transmitter action of acetylcholine. Gallamine has a parasympatholytic effect on the cardiac vagus nerve which causes tachycardia and occasionally hypertension. Very high doses cause histamine release.

Additional recommended knowledge

Gallamine is commonly used to stabilize muscle contractions during surgical procedures.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Gallamine". A list of authors is available in Wikipedia.
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