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List of EC numbers (EC 1)



This list contains a list of EC numbers for the first group, EC 1, oxidoreducatases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology.

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Contents

EC 1.1 Acting on the CH-OH group of donors

EC 1.1.1 With NAD or NADP as acceptor

  • EC 1.1.1.1: alcohol dehydrogenase
  • EC 1.1.1.2: alcohol dehydrogenase (NADP+)
  • EC 1.1.1.3: homoserine dehydrogenase
  • EC 1.1.1.4: (R,R)-butanediol dehydrogenase
  • EC 1.1.1.5: acetoin dehydrogenase
  • EC 1.1.1.6: glycerol dehydrogenase
  • EC 1.1.1.7: propanediol-phosphate dehydrogenase
  • EC 1.1.1.8: glycerol-3-phosphate dehydrogenase (NAD+)
  • EC 1.1.1.9: D-xylulose reductase
  • EC 1.1.1.10: L-xylulose reductase
  • EC 1.1.1.11: D-arabinitol 4-dehydrogenase
  • EC 1.1.1.12: L-arabinitol 4-dehydrogenase
  • EC 1.1.1.13: L-arabinitol 2-dehydrogenase
  • EC 1.1.1.14: L-iditol 2-dehydrogenase
  • EC 1.1.1.15: D-iditol 2-dehydrogenase
  • EC 1.1.1.16: galactitol 2-dehydrogenase
  • EC 1.1.1.17: mannitol-1-phosphate 5-dehydrogenase
  • EC 1.1.1.18: inositol 2-dehydrogenase
  • EC 1.1.1.19: L-glucuronate reductase
  • EC 1.1.1.20: glucuronolactone reductase
  • EC 1.1.1.21: aldehyde reductase
  • EC 1.1.1.22: UDP-glucose 6-dehydrogenase
  • EC 1.1.1.23: histidinol dehydrogenase
  • EC 1.1.1.24: quinate dehydrogenase
  • EC 1.1.1.25: shikimate dehydrogenase
  • EC 1.1.1.26: glyoxylate reductase
  • EC 1.1.1.27: L-lactate dehydrogenase
  • EC 1.1.1.28: D-lactate dehydrogenase
  • EC 1.1.1.29: glycerate dehydrogenase
  • EC 1.1.1.30: 3-hydroxybutyrate dehydrogenase
  • EC 1.1.1.31: 3-hydroxyisobutyrate dehydrogenase
  • EC 1.1.1.32: mevaldate reductase
  • EC 1.1.1.33: mevaldate reductase (NADPH)
  • EC 1.1.1.34: hydroxymethylglutaryl-CoA reductase (NADPH)
  • EC 1.1.1.35: 3-hydroxyacyl-CoA dehydrogenase
  • EC 1.1.1.36: acetoacetyl-CoA reductase
  • EC 1.1.1.37: malate dehydrogenase
  • EC 1.1.1.38: malate dehydrogenase (oxaloacetate-decarboxylating)
  • EC 1.1.1.39: malate dehydrogenase (decarboxylating)
  • EC 1.1.1.40: malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+)
  • EC 1.1.1.41: isocitrate dehydrogenase (NAD+)
  • EC 1.1.1.42: isocitrate dehydrogenase (NADP+)
  • EC 1.1.1.43: phosphogluconate 2-dehydrogenase
  • EC 1.1.1.44: phosphogluconate dehydrogenase (decarboxylating)
  • EC 1.1.1.45: L-gulonate 3-dehydrogenase
  • EC 1.1.1.46: L-arabinose 1-dehydrogenase
  • EC 1.1.1.47: glucose 1-dehydrogenase
  • EC 1.1.1.48: galactose 1-dehydrogenase
  • EC 1.1.1.49: glucose-6-phosphate dehydrogenase
  • EC 1.1.1.50: 3a-hydroxysteroid dehydrogenase (B-specific)
  • EC 1.1.1.51: 3(or 17)b-hydroxysteroid dehydrogenase
  • EC 1.1.1.52: 3a-hydroxycholanate dehydrogenase
  • EC 1.1.1.53: 3a(or 20b)-hydroxysteroid dehydrogenase
  • EC 1.1.1.54: allyl-alcohol dehydrogenase
  • EC 1.1.1.55: lactaldehyde reductase (NADPH)
  • EC 1.1.1.56: ribitol 2-dehydrogenase
  • EC 1.1.1.57: fructuronate reductase
  • EC 1.1.1.58: tagaturonate reductase
  • EC 1.1.1.59: 3-hydroxypropionate dehydrogenase
  • EC 1.1.1.60: 2-hydroxy-3-oxopropionate reductase
  • EC 1.1.1.61: 4-hydroxybutyrate dehydrogenase
  • EC 1.1.1.62: estradiol 17b-dehydrogenase
  • EC 1.1.1.63: testosterone 17b-dehydrogenase
  • EC 1.1.1.64: testosterone 17b-dehydrogenase (NADP+)
  • EC 1.1.1.65: pyridoxine 4-dehydrogenase
  • EC 1.1.1.66: w-hydroxydecanoate dehydrogenase
  • EC 1.1.1.67: mannitol 2-dehydrogenase
  • EC 1.1.1.68: now *EC 1.7.99.5
  • EC 1.1.1.69: gluconate 5-dehydrogenase
  • EC 1.1.1.70: deleted, included in *EC 1.2.1.3
  • EC 1.1.1.71: alcohol dehydrogenase (NAD(P)+)
  • EC 1.1.1.72: glycerol dehydrogenase (NADP+)
  • EC 1.1.1.73: octanol dehydrogenase
  • EC 1.1.1.74: deleted
  • EC 1.1.1.75: (R)-aminopropanol dehydrogenase
  • EC 1.1.1.76: (S,S)-butanediol dehydrogenase
  • EC 1.1.1.77: lactaldehyde reductase
  • EC 1.1.1.78: methylglyoxal reductase (NADH-dependent)
  • EC 1.1.1.79: glyoxylate reductase (NADP+)
  • EC 1.1.1.80: isopropanol dehydrogenase (NADP+)
  • EC 1.1.1.81: hydroxypyruvate reductase
  • EC 1.1.1.82: malate dehydrogenase (NADP+)
  • EC 1.1.1.83: D-malate dehydrogenase (decarboxylating)
  • EC 1.1.1.84: dimethylmalate dehydrogenase
  • EC 1.1.1.85: 3-isopropylmalate dehydrogenase
  • EC 1.1.1.86: ketol-acid reductoisomerase
  • EC 1.1.1.87: homoisocitrate dehydrogenase
  • EC 1.1.1.88: hydroxymethylglutaryl-CoA reductase
  • EC 1.1.1.89: deleted, included in *EC 1.1.1.86
  • EC 1.1.1.90: aryl-alcohol dehydrogenase
  • EC 1.1.1.91: aryl-alcohol dehydrogenase (NADP+)
  • EC 1.1.1.92: oxaloglycolate reductase (decarboxylating)
  • EC 1.1.1.93: tartrate dehydrogenase
  • EC 1.1.1.94: glycerol-3-phosphate dehydrogenase (NAD(P)+)
  • EC 1.1.1.95: phosphoglycerate dehydrogenase
  • EC 1.1.1.96: diiodophenylpyruvate reductase
  • EC 1.1.1.97: 3-hydroxybenzyl-alcohol dehydrogenase
  • EC 1.1.1.98: (R)-2-hydroxy-fatty-acid dehydrogenase
  • EC 1.1.1.99: (S)-2-hydroxy-fatty-acid dehydrogenase
  • EC 1.1.1.100: 3-oxoacyl-(acyl-carrier-protein) reductase
  • EC 1.1.1.101: acylglycerone-phosphate reductase
  • EC 1.1.1.102: 3-dehydrosphinganine reductase
  • EC 1.1.1.103: L-threonine 3-dehydrogenase
  • EC 1.1.1.104: 4-oxoproline reductase
  • EC 1.1.1.105: retinol dehydrogenase
  • EC 1.1.1.106: pantoate 4-dehydrogenase
  • EC 1.1.1.107: pyridoxal 4-dehydrogenase
  • EC 1.1.1.108: carnitine 3-dehydrogenase
  • EC 1.1.1.109: now *EC 1.3.1.28
  • EC 1.1.1.110: indolelactate dehydrogenase
  • EC 1.1.1.111: 3-(imidazol-5-yl)lactate dehydrogenase
  • EC 1.1.1.112: indanol dehydrogenase
  • EC 1.1.1.113: L-xylose 1-dehydrogenase
  • EC 1.1.1.114: apiose 1-reductase
  • EC 1.1.1.115: ribose 1-dehydrogenase (NADP+)
  • EC 1.1.1.116: D-arabinose 1-dehydrogenase
  • EC 1.1.1.117: D-arabinose 1-dehydrogenase (NAD(P)+)
  • EC 1.1.1.118: glucose 1-dehydrogenase (NAD+)
  • EC 1.1.1.119: glucose 1-dehydrogenase (NADP+)
  • EC 1.1.1.120: galactose 1-dehydrogenase (NADP+)
  • EC 1.1.1.121: aldose 1-dehydrogenase
  • EC 1.1.1.122: D-threo-aldose 1-dehydrogenase
  • EC 1.1.1.123: sorbose 5-dehydrogenase (NADP+)
  • EC 1.1.1.124: fructose 5-dehydrogenase (NADP+)
  • EC 1.1.1.125: 2-deoxy-D-gluconate 3-dehydrogenase
  • EC 1.1.1.126: 2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase
  • EC 1.1.1.127: 2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
  • EC 1.1.1.128: L-idonate 2-dehydrogenase
  • EC 1.1.1.129: L-threonate 3-dehydrogenase
  • EC 1.1.1.130: 3-dehydro-L-gulonate 2-dehydrogenase
  • EC 1.1.1.131: mannuronate reductase
  • EC 1.1.1.132: GDP-mannose 6-dehydrogenase
  • EC 1.1.1.133: dTDP-4-dehydrorhamnose reductase
  • EC 1.1.1.134: dTDP-6-deoxy-L-talose 4-dehydrogenase
  • EC 1.1.1.135: GDP-6-deoxy-D-talose 4-dehydrogenase
  • EC 1.1.1.136: UDP-N-acetylglucosamine 6-dehydrogenase
  • EC 1.1.1.137: ribitol-5-phosphate 2-dehydrogenase
  • EC 1.1.1.138: mannitol 2-dehydrogenase (NADP+)
  • EC 1.1.1.139: deleted, included in *EC 1.1.1.21
  • EC 1.1.1.140: sorbitol-6-phosphate 2-dehydrogenase
  • EC 1.1.1.141: 15-hydroxyprostaglandin dehydrogenase (NAD+)
  • EC 1.1.1.142: D-pinitol dehydrogenase
  • EC 1.1.1.143: sequoyitol dehydrogenase
  • EC 1.1.1.144: perillyl-alcohol dehydrogenase
  • EC 1.1.1.145: 3b-hydroxy-D5-steroid dehydrogenase
  • EC 1.1.1.146: 11b-hydroxysteroid dehydrogenase
  • EC 1.1.1.147: 16a-hydroxysteroid dehydrogenase
  • EC 1.1.1.148: estradiol 17a-dehydrogenase
  • EC 1.1.1.149: 20a-hydroxysteroid dehydrogenase
  • EC 1.1.1.150: 21-hydroxysteroid dehydrogenase (NAD+)
  • EC 1.1.1.151: 21-hydroxysteroid dehydrogenase (NADP+)
  • EC 1.1.1.152: 3a-hydroxy-5b-androstane-17-one 3a-dehydrogenase
  • EC 1.1.1.153: sepiapterin reductase
  • EC 1.1.1.154: ureidoglycolate dehydrogenase
  • EC 1.1.1.155: identical to *EC 1.1.1.87
  • EC 1.1.1.156: glycerol 2-dehydrogenase (NADP+)
  • EC 1.1.1.157: 3-hydroxybutyryl-CoA dehydrogenase
  • EC 1.1.1.158: UDP-N-acetylmuramate dehydrogenase
  • EC 1.1.1.159: 7a-hydroxysteroid dehydrogenase
  • EC 1.1.1.160: dihydrobunolol dehydrogenase
  • EC 1.1.1.161: cholestanetetraol 26-dehydrogenase
  • EC 1.1.1.162: erythrulose reductase
  • EC 1.1.1.163: cyclopentanol dehydrogenase
  • EC 1.1.1.164: hexadecanol dehydrogenase
  • EC 1.1.1.165: 2-alkyn-1-ol dehydrogenase
  • EC 1.1.1.166: hydroxycyclohexanecarboxylate dehydrogenase
  • EC 1.1.1.167: hydroxymalonate dehydrogenase
  • EC 1.1.1.168: 2-dehydropantolactone reductase (A-specific)
  • EC 1.1.1.169: 2-dehydropantoate 2-reductase
  • EC 1.1.1.170: 3b-hydroxy-4a-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating)
  • EC 1.1.1.171: now *EC 1.5.1.20
  • EC 1.1.1.172: 2-oxoadipate reductase
  • EC 1.1.1.173: L-rhamnose 1-dehydrogenase
  • EC 1.1.1.174: cyclohexane-1,2-diol dehydrogenase
  • EC 1.1.1.175: D-xylose 1-dehydrogenase
  • EC 1.1.1.176: 12a-hydroxysteroid dehydrogenase
  • EC 1.1.1.177: glycerol-3-phosphate 1-dehydrogenase (NADP+)
  • EC 1.1.1.178: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase
  • EC 1.1.1.179: D-xylose 1-dehydrogenase (NADP+)
  • EC 1.1.1.180: deleted, included in *EC 1.1.1.131
  • EC 1.1.1.181: cholest-5-ene-3b,7a-diol 3b-dehydrogenase
  • EC 1.1.1.182: deleted, included in *EC 1.1.1.198, *EC 1.1.1.227 and *EC 1.1.1.228
  • EC 1.1.1.183: geraniol dehydrogenase
  • EC 1.1.1.184: carbonyl reductase (NADPH)
  • EC 1.1.1.185: L-glycol dehydrogenase
  • EC 1.1.1.186: dTDP-galactose 6-dehydrogenase
  • EC 1.1.1.187: GDP-4-dehydro-D-rhamnose reductase
  • EC 1.1.1.188: prostaglandin-F synthase
  • EC 1.1.1.189: prostaglandin-E2 9-reductase
  • EC 1.1.1.190: indole-3-acetaldehyde reductase (NADH)
  • EC 1.1.1.191: indole-3-acetaldehyde reductase (NADPH)
  • EC 1.1.1.192: long-chain-alcohol dehydrogenase
  • EC 1.1.1.193: 5-amino-6-(5-phosphoribosylamino)uracil reductase
  • EC 1.1.1.194: coniferyl-alcohol dehydrogenase
  • EC 1.1.1.195: cinnamyl-alcohol dehydrogenase
  • EC 1.1.1.196: 15-hydroxyprostaglandin-D dehydrogenase (NADP+)
  • EC 1.1.1.197: 15-hydroxyprostaglandin dehydrogenase (NADP+)
  • EC 1.1.1.198: (+)-borneol dehydrogenase
  • EC 1.1.1.199: (S)-usnate reductase
  • EC 1.1.1.200: aldose-6-phosphate reductase (NADPH)
  • EC 1.1.1.201: 7b-hydroxysteroid dehydrogenase (NADP+)
  • EC 1.1.1.202: 1,3-propanediol dehydrogenase
  • EC 1.1.1.203: uronate dehydrogenase
  • EC 1.1.1.204: now *EC 1.17.1.4
  • EC 1.1.1.205: IMP dehydrogenase
  • EC 1.1.1.206: tropine dehydrogenase
  • EC 1.1.1.207: (-)-menthol dehydrogenase
  • EC 1.1.1.208: (+)-neomenthol dehydrogenase
  • EC 1.1.1.209: 3(or 17)a-hydroxysteroid dehydrogenase
  • EC 1.1.1.210: 3b(or 20a)-hydroxysteroid dehydrogenase
  • EC 1.1.1.211: long-chain-3-hydroxyacyl-CoA dehydrogenase
  • EC 1.1.1.212: 3-oxoacyl-(acyl-carrier-protein) reductase (NADH)
  • EC 1.1.1.213: 3a-hydroxysteroid dehydrogenase (A-specific)
  • EC 1.1.1.214: 2-dehydropantolactone reductase (B-specific)
  • EC 1.1.1.215: gluconate 2-dehydrogenase
  • EC 1.1.1.216: farnesol dehydrogenase
  • EC 1.1.1.217: benzyl-2-methyl-hydroxybutyrate dehydrogenase
  • EC 1.1.1.218: morphine 6-dehydrogenase
  • EC 1.1.1.219: dihydrokaempferol 4-reductase
  • EC 1.1.1.220: 6-pyruvoyltetrahydropterin 2'-reductase
  • EC 1.1.1.221: vomifoliol 4'-dehydrogenase
  • EC 1.1.1.222: (R)-4-hydroxyphenyllactate dehydrogenase
  • EC 1.1.1.223: isopiperitenol dehydrogenase
  • EC 1.1.1.224: mannose-6-phosphate 6-reductase
  • EC 1.1.1.225: chlordecone reductase
  • EC 1.1.1.226: 4-hydroxycyclohexanecarboxylate dehydrogenase
  • EC 1.1.1.227: (-)-borneol dehydrogenase
  • EC 1.1.1.228: (+)-sabinol dehydrogenase
  • EC 1.1.1.229: diethyl 2-methyl-3-oxosuccinate reductase
  • EC 1.1.1.230: 3a-hydroxyglycyrrhetinate dehydrogenase
  • EC 1.1.1.231: 15-hydroxyprostaglandin-I dehydrogenase (NADP+)
  • EC 1.1.1.232: 15-hydroxyicosatetraenoate dehydrogenase
  • EC 1.1.1.233: N-acylmannosamine 1-dehydrogenase
  • EC 1.1.1.234: flavanone 4-reductase
  • EC 1.1.1.235: 8-oxocoformycin reductase
  • EC 1.1.1.236: tropinone reductase
  • EC 1.1.1.237: hydroxyphenylpyruvate reductase
  • EC 1.1.1.238: 12b-hydroxysteroid dehydrogenase
  • EC 1.1.1.239: 3a(17b)-hydroxysteroid dehydrogenase (NAD+)
  • EC 1.1.1.240: N-acetylhexosamine 1-dehydrogenase
  • EC 1.1.1.241: 6-endo-hydroxycineole dehydrogenase
  • EC 1.1.1.242: zeatin reductase — now *EC 1.3.1.69
  • EC 1.1.1.243: carveol dehydrogenase
  • EC 1.1.1.244: methanol dehydrogenase
  • EC 1.1.1.245: cyclohexanol dehydrogenase
  • EC 1.1.1.246: pterocarpin synthase
  • EC 1.1.1.247: codeinone reductase (NADPH)
  • EC 1.1.1.248: salutaridine reductase (NADPH)
  • EC 1.1.1.249: reinstated as *EC 2.5.1.46
  • EC 1.1.1.250: D-arabinitol 2-dehydrogenase
  • EC 1.1.1.251: galactitol-1-phosphate 5-dehydrogenase
  • EC 1.1.1.252: tetrahydroxynaphthalene reductase
  • EC 1.1.1.253: now *EC 1.5.1.33
  • EC 1.1.1.254: (S)-carnitine 3-dehydrogenase
  • EC 1.1.1.255: mannitol dehydrogenase
  • EC 1.1.1.256: fluoren-9-ol dehydrogenase
  • EC 1.1.1.257: 4-(hydroxymethyl)benzenesulfonate dehydrogenase
  • EC 1.1.1.258: 6-hydroxyhexanoate dehydrogenase
  • EC 1.1.1.259: 3-hydroxypimeloyl-CoA dehydrogenase
  • EC 1.1.1.260: sulcatone reductase
  • EC 1.1.1.261: glycerol-1-phosphate dehydrogenase (NAD(P)+)
  • EC 1.1.1.262: 4-hydroxythreonine-4-phosphate dehydrogenase
  • EC 1.1.1.263: 1,5-anhydro-D-fructose reductase
  • EC 1.1.1.264: L-idonate 5-dehydrogenase
  • EC 1.1.1.265: 3-methylbutanal reductase
  • EC 1.1.1.266: dTDP-4-dehydro-6-deoxyglucose reductase
  • EC 1.1.1.267: 1-deoxy-D-xylulose-5-phosphate reductoisomerase
  • EC 1.1.1.268: 2-(R)-hydroxypropyl-CoM dehydrogenase
  • EC 1.1.1.269: 2-(S)-hydroxypropyl-CoM dehydrogenase
  • EC 1.1.1.270: 3-keto-steroid reductase
  • EC 1.1.1.271: GDP-L-fucose synthase
  • EC 1.1.1.272: (R)-2-hydroxyacid dehydrogenase
  • EC 1.1.1.273: vellosimine dehydrogenase
  • EC 1.1.1.274: 2,5-didehydrogluconate reductase
  • EC 1.1.1.275: (+)-trans-carveol dehydrogenase
  • EC 1.1.1.276: serine 3-dehydrogenase
  • EC 1.1.1.277: 3b-hydroxy-5b-steroid dehydrogenase
  • EC 1.1.1.278: 3b-hydroxy-5a-steroid dehydrogenase
  • EC 1.1.1.279: (R)-3-hydroxyacid ester dehydrogenase
  • EC 1.1.1.280: (S)-3-hydroxyacid ester dehydrogenase
  • EC 1.1.1.281: GDP-4-dehydro-6-deoxy-D-mannose reductase
  • EC 1.1.1.282: quinate/shikimate dehydrogenase
  • EC 1.1.1.283: methylglyoxal reductase (NADPH-dependent)
  • EC 1.1.1.284: S-(hydroxymethyl)glutathione dehydrogenase
  • EC 1.1.1.285: 3"-deamino-3"-oxonicotianamine reductase
  • EC 1.1.1.286: isocitrate—homoisocitrate dehydrogenase
  • EC 1.1.1.287: D-arabinitol dehydrogenase (NADP+)

EC 1.1.2 With a cytochrome as acceptor

  • EC 1.1.2.1: now *EC 1.1.99.5
  • EC 1.1.2.2: mannitol dehydrogenase (cytochrome)
  • EC 1.1.2.3: L-lactate dehydrogenase (cytochrome)
  • EC 1.1.2.4: D-lactate dehydrogenase (cytochrome)
  • EC 1.1.2.5: D-lactate dehydrogenase (cytochrome c-553)

EC 1.1.3 With oxygen as acceptor

  • EC 1.1.3.1: deleted, included in *EC 1.1.3.15
  • EC 1.1.3.2: now *EC 1.13.12.4
  • EC 1.1.3.3: malate oxidase
  • EC 1.1.3.4: glucose oxidase
  • EC 1.1.3.5: hexose oxidase
  • EC 1.1.3.6: cholesterol oxidase
  • EC 1.1.3.7: aryl-alcohol oxidase
  • EC 1.1.3.8: L-gulonolactone oxidase
  • EC 1.1.3.9: galactose oxidase
  • EC 1.1.3.10: pyranose oxidase
  • EC 1.1.3.11: L-sorbose oxidase
  • EC 1.1.3.12: pyridoxine 4-oxidase
  • EC 1.1.3.13: alcohol oxidase
  • EC 1.1.3.14: catechol oxidase (dimerizing)
  • EC 1.1.3.15: (S)-2-hydroxy-acid oxidase
  • EC 1.1.3.16: ecdysone oxidase
  • EC 1.1.3.17: choline oxidase
  • EC 1.1.3.18: Secondary-alcohol oxidase
  • EC 1.1.3.19: 4-hydroxymandelate oxidase
  • EC 1.1.3.20: long-chain-alcohol oxidase
  • EC 1.1.3.21: glycerol-3-phosphate oxidase
  • EC 1.1.3.22: now *EC 1.17.3.2
  • EC 1.1.3.23: thiamin oxidase
  • EC 1.1.3.24: L-galactonolactone oxidase
  • EC 1.1.3.25: now included with *EC 1.1.99.18
  • EC 1.1.3.26: now *EC 1.21.3.2
  • EC 1.1.3.27: hydroxyphytanate oxidase
  • EC 1.1.3.28: nucleoside oxidase
  • EC 1.1.3.29: N-acylhexosamine oxidase
  • EC 1.1.3.30: polyvinyl-alcohol oxidase
  • EC 1.1.3.31: deleted
  • EC 1.1.3.32: now *EC 1.14.21.1
  • EC 1.1.3.33: now *EC 1.14.21.2
  • EC 1.1.3.34: now *EC 1.14.21.3
  • EC 1.1.3.35: now *EC 1.14.21.4
  • EC 1.1.3.36: now *EC 1.14.21.5
  • EC 1.1.3.37: D-arabinono-1,4-lactone oxidase
  • EC 1.1.3.38: vanillyl-alcohol oxidase
  • EC 1.1.3.39: nucleoside oxidase (H2O2-forming)
  • EC 1.1.3.40: D-mannitol oxidase
  • EC 1.1.3.41: xylitol oxidase

EC 1.1.4 With a disulfide as acceptor

  • EC 1.1.4.1: vitamin-K-epoxide reductase (warfarin-sensitive)
  • EC 1.1.4.2: vitamin-K-epoxide reductase (warfarin-insensitive)

EC 1.1.5 With a quinone or similar compound as acceptor

  • EC 1.1.5.1: deleted, see EC 1.1.99.18 cellobiose dehydrogenase (acceptor)
  • EC 1.1.5.2: quinoprotein glucose dehydrogenase

EC 1.1.99 With other acceptors

  • EC 1.1.99.1: choline dehydrogenase
  • EC 1.1.99.2: 2-hydroxyglutarate dehydrogenase
  • EC 1.1.99.3: gluconate 2-dehydrogenase (acceptor)
  • EC 1.1.99.4: dehydrogluconate dehydrogenase
  • EC 1.1.99.5: glycerol-3-phosphate dehydrogenase
  • EC 1.1.99.6: D-2-hydroxy-acid dehydrogenase
  • EC 1.1.99.7: lactate—malate transhydrogenase
  • EC 1.1.99.8: alcohol dehydrogenase (acceptor)
  • EC 1.1.99.9: pyridoxine 5-dehydrogenase
  • EC 1.1.99.10: glucose dehydrogenase (acceptor)
  • EC 1.1.99.11: fructose 5-dehydrogenase
  • EC 1.1.99.12: sorbose dehydrogenase
  • EC 1.1.99.13: glucoside 3-dehydrogenase
  • EC 1.1.99.14: glycolate dehydrogenase
  • EC 1.1.99.15: now *EC 1.7.99.5
  • EC 1.1.99.16: malate dehydrogenase (acceptor)
  • EC 1.1.99.17: now *EC 1.1.5.2
  • EC 1.1.99.18: cellobiose dehydrogenase (acceptor)
  • EC 1.1.99.19: uracil dehydrogenase
  • EC 1.1.99.20: alkan-1-ol dehydrogenase (acceptor)
  • EC 1.1.99.21: D-sorbitol dehydrogenase (acceptor)
  • EC 1.1.99.22: glycerol dehydrogenase (acceptor)
  • EC 1.1.99.23: polyvinyl-alcohol dehydrogenase (acceptor)
  • EC 1.1.99.24: hydroxyacid-oxoacid transhydrogenase
  • EC 1.1.99.25: quinate dehydrogenase (pyrroloquinoline-quinone)
  • EC 1.1.99.26: 3-hydroxycyclohexanone dehydrogenase
  • EC 1.1.99.27: (R)-pantolactone dehydrogenase (flavin)
  • EC 1.1.99.28: glucose-fructose oxidoreductase
  • EC 1.1.99.29: pyranose dehydrogenase (acceptor)
  • EC 1.1.99.30: 2-oxoacid reductase

EC 1.2 Acting on the aldehyde or oxo group of donors

EC 1.2.1 With NAD or NADP as acceptor

  • EC 1.2.1.1: deleted, replaced by *EC 1.1.1.284 and *EC 4.4.1.22
  • EC 1.2.1.2: formate dehydrogenase
  • EC 1.2.1.3: aldehyde dehydrogenase (NAD+)
  • EC 1.2.1.4: aldehyde dehydrogenase (NADP+)
  • EC 1.2.1.5: aldehyde dehydrogenase (NAD(P)+)
  • EC 1.2.1.6: deleted
  • EC 1.2.1.7: benzaldehyde dehydrogenase (NADP+)
  • EC 1.2.1.8: betaine-aldehyde dehydrogenase
  • EC 1.2.1.9: glyceraldehyde-3-phosphate dehydrogenase (NADP+)
  • EC 1.2.1.10: acetaldehyde dehydrogenase (acetylating)
  • EC 1.2.1.11: aspartate-semialdehyde dehydrogenase
  • EC 1.2.1.12: glyceraldehyde-3-phosphate dehydrogenase (phosphorylating)
  • EC 1.2.1.13: glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating)
  • EC 1.2.1.14: now *EC 1.1.1.205
  • EC 1.2.1.15: malonate-semialdehyde dehydrogenase
  • EC 1.2.1.16: succinate-semialdehyde dehydrogenase (NAD(P)+)
  • EC 1.2.1.17: glyoxylate dehydrogenase (acylating)
  • EC 1.2.1.18: malonate-semialdehyde dehydrogenase (acetylating)
  • EC 1.2.1.19: aminobutyraldehyde dehydrogenase
  • EC 1.2.1.20: glutarate-semialdehyde dehydrogenase
  • EC 1.2.1.21: glycolaldehyde dehydrogenase
  • EC 1.2.1.22: lactaldehyde dehydrogenase
  • EC 1.2.1.23: 2-oxoaldehyde dehydrogenase (NAD+)
  • EC 1.2.1.24: succinate-semialdehyde dehydrogenase
  • EC 1.2.1.25: 2-oxoisovalerate dehydrogenase (acylating)
  • EC 1.2.1.26: 2,5-dioxovalerate dehydrogenase
  • EC 1.2.1.27: methylmalonate-semialdehyde dehydrogenase (acylating)
  • EC 1.2.1.28: benzaldehyde dehydrogenase (NAD+)
  • EC 1.2.1.29: aryl-aldehyde dehydrogenase
  • EC 1.2.1.30: aryl-aldehyde dehydrogenase (NADP+)
  • EC 1.2.1.31: L-aminoadipate-semialdehyde dehydrogenase
  • EC 1.2.1.32: aminomuconate-semialdehyde dehydrogenase
  • EC 1.2.1.33: (R)-dehydropantoate dehydrogenase
  • EC 1.2.1.34: deleted, included in *EC 1.1.1.131
  • EC 1.2.1.35: now *EC 1.1.1.203
  • EC 1.2.1.36: retinal dehydrogenase
  • EC 1.2.1.37: now *EC 1.1.1.204
  • EC 1.2.1.38: N-acetyl-g-glutamyl-phosphate reductase
  • EC 1.2.1.39: phenylacetaldehyde dehydrogenase
  • EC 1.2.1.40: 3a,7a,12a-trihydroxycholestan-26-al 26-oxidoreductase
  • EC 1.2.1.41: glutamate-5-semialdehyde dehydrogenase
  • EC 1.2.1.42: hexadecanal dehydrogenase (acylating)
  • EC 1.2.1.43: formate dehydrogenase (NADP+)
  • EC 1.2.1.44: cinnamoyl-CoA reductase
  • EC 1.2.1.45: 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase
  • EC 1.2.1.46: formaldehyde dehydrogenase
  • EC 1.2.1.47: 4-trimethylammoniobutyraldehyde dehydrogenase
  • EC 1.2.1.48: long-chain-aldehyde dehydrogenase
  • EC 1.2.1.49: 2-oxoaldehyde dehydrogenase (NADP+)
  • EC 1.2.1.50: long-chain-fatty-acyl-CoA reductase
  • EC 1.2.1.51: pyruvate dehydrogenase (NADP+)
  • EC 1.2.1.52: oxoglutarate dehydrogenase (NADP+)
  • EC 1.2.1.53: 4-hydroxyphenylacetaldehyde dehydrogenase
  • EC 1.2.1.54: g-guanidinobutyraldehyde dehydrogenase
  • EC 1.2.1.55: now *EC 1.1.1.279
  • EC 1.2.1.56: now *EC 1.1.1.280
  • EC 1.2.1.57: butanal dehydrogenase
  • EC 1.2.1.58: phenylglyoxylate dehydrogenase (acylating)
  • EC 1.2.1.59: glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+)
  • EC 1.2.1.60: 5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase
  • EC 1.2.1.61: 4-hydroxymuconic-semialdehyde dehydrogenase
  • EC 1.2.1.62: 4-formylbenzenesulfonate dehydrogenase
  • EC 1.2.1.63: 6-oxohexanoate dehydrogenase
  • EC 1.2.1.64: 4-hydroxybenzaldehyde dehydrogenase
  • EC 1.2.1.65: salicylaldehyde dehydrogenase
  • EC 1.2.1.66: mycothiol-dependent formaldehyde dehydrogenase
  • EC 1.2.1.67: vanillin dehydrogenase
  • EC 1.2.1.68: coniferyl-aldehyde dehydrogenase
  • EC 1.2.1.69: fluoroacetaldehyde dehydrogenase
  • EC 1.2.1.70: glutamyl-tRNA reductase

EC 1.2.2 With a cytochrome as acceptor

  • EC 1.2.2.1: formate dehydrogenase (cytochrome)
  • EC 1.2.2.2: pyruvate dehydrogenase (cytochrome)
  • EC 1.2.2.3: formate dehydrogenase (cytochrome-c-553)
  • EC 1.2.2.4: carbon-monoxide dehydrogenase (cytochrome b-561)

EC 1.2.3 With oxygen as acceptor

  • EC 1.2.3.1: aldehyde oxidase
  • EC 1.2.3.2: now *EC 1.1.3.22
  • EC 1.2.3.3: pyruvate oxidase
  • EC 1.2.3.4: oxalate oxidase
  • EC 1.2.3.5: glyoxylate oxidase
  • EC 1.2.3.6: pyruvate oxidase (CoA-acetylating)
  • EC 1.2.3.7: indole-3-acetaldehyde oxidase
  • EC 1.2.3.8: pyridoxal oxidase
  • EC 1.2.3.9: aryl-aldehyde oxidase
  • EC 1.2.3.10: deleted
  • EC 1.2.3.11: retinal oxidase
  • EC 1.2.3.12: now *EC 1.14.13.82
  • EC 1.2.3.13: 4-hydroxyphenylpyruvate oxidase

EC 1.2.4 With a disulfide as acceptor

EC 1.2.7 With an iron-sulfur protein as acceptor

  • EC 1.2.7.1: pyruvate synthase
  • EC 1.2.7.2: 2-oxobutyrate synthase
  • EC 1.2.7.3: 2-oxoglutarate synthase
  • EC 1.2.7.4: carbon-monoxide dehydrogenase (ferredoxin)
  • EC 1.2.7.5: aldehyde ferredoxin oxidoreductase
  • EC 1.2.7.6: glyceraldehyde-3-phosphate dehydrogenase (ferredoxin)
  • EC 1.2.7.7: 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
  • EC 1.2.7.8: indolepyruvate ferredoxin oxidoreductase
  • EC 1.2.7.9: deleted, identical to *EC 1.2.7.3

EC 1.2.99 With other acceptors

  • EC 1.2.99.1: now *EC 1.1.99.19
  • EC 1.2.99.2: carbon-monoxide dehydrogenase (acceptor)
  • EC 1.2.99.3: aldehyde dehydrogenase (pyrroloquinoline-quinone)
  • EC 1.2.99.4: formaldehyde dismutase
  • EC 1.2.99.5: formylmethanofuran dehydrogenase
  • EC 1.2.99.6: carboxylate reductase
  • EC 1.2.99.7: aldehyde dehydrogenase (FAD-independent)

EC 1.3 Acting on the CH-CH group of donors

EC 1.3.1 With NAD or NADP as acceptor

  • EC 1.3.1.1: dihydrouracil dehydrogenase (NAD+)
  • EC 1.3.1.2: dihydropyrimidine dehydrogenase (NADP+)
  • EC 1.3.1.3: cortisone b-reductase
  • EC 1.3.1.4: cortisone a-reductase
  • EC 1.3.1.5: cucurbitacin D23-reductase
  • EC 1.3.1.6: fumarate reductase (NADH)
  • EC 1.3.1.7: meso-tartrate dehydrogenase
  • EC 1.3.1.8: acyl-CoA dehydrogenase (NADP+)
  • EC 1.3.1.9: enoyl-(acyl-carrier-protein) reductase (NADH)
  • EC 1.3.1.10: enoyl-(acyl-carrier-protein) reductase (NADPH, B-specific)
  • EC 1.3.1.11: 2-coumarate reductase
  • EC 1.3.1.12: prephenate dehydrogenase
  • EC 1.3.1.13: prephenate dehydrogenase (NADP+)
  • EC 1.3.1.14: orotate reductase (NADH)
  • EC 1.3.1.15: orotate reductase (NADPH)
  • EC 1.3.1.16: b-nitroacrylate reductase
  • EC 1.3.1.17: 3-methyleneoxindole reductase
  • EC 1.3.1.18: kynurenate-7,8-dihydrodiol dehydrogenase
  • EC 1.3.1.19: cis-1,2-dihydrobenzene-1,2-diol dehydrogenase
  • EC 1.3.1.20: trans-1,2-dihydrobenzene-1,2-diol dehydrogenase
  • EC 1.3.1.21: 7-dehydrocholesterol reductase
  • EC 1.3.1.22: cholestenone 5a-reductase
  • EC 1.3.1.23: cholestenone 5b-reductase
  • EC 1.3.1.24: biliverdin reductase
  • EC 1.3.1.25: 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase
  • EC 1.3.1.26: dihydrodipicolinate reductase
  • EC 1.3.1.27: 2-hexadecenal reductase
  • EC 1.3.1.28: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
  • EC 1.3.1.29: cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase
  • EC 1.3.1.30: progesterone 5a-reductase
  • EC 1.3.1.31: 2-enoate reductase
  • EC 1.3.1.32: maleylacetate reductase
  • EC 1.3.1.33: protochlorophyllide reductase
  • EC 1.3.1.34: 2,4-dienoyl-CoA reductase (NADPH)
  • EC 1.3.1.35: phosphatidylcholine desaturase
  • EC 1.3.1.36: geissoschizine dehydrogenase
  • EC 1.3.1.37: cis-2-enoyl-CoA reductase (NADPH)
  • EC 1.3.1.38: trans-2-enoyl-CoA reductase (NADPH)
  • EC 1.3.1.39: enoyl-(acyl-carrier-protein) reductase (NADPH, A-specific)
  • EC 1.3.1.40: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase
  • EC 1.3.1.41: xanthommatin reductase
  • EC 1.3.1.42: 12-oxophytodienoate reductase
  • EC 1.3.1.43: arogenate dehydrogenase
  • EC 1.3.1.44: trans-2-enoyl-CoA reductase (NAD+)
  • EC 1.3.1.45: 2'-hydroxyisoflavone reductase
  • EC 1.3.1.46: biochanin-A reductase
  • EC 1.3.1.47: a-santonin 1,2-reductase
  • EC 1.3.1.48: 15-oxoprostaglandin 13-oxidase
  • EC 1.3.1.49: cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase
  • EC 1.3.1.50: now *EC 1.1.1.252
  • EC 1.3.1.51: 2'-hydroxydaidzein reductase
  • EC 1.3.1.52: 2-methyl-branched-chain-enoyl-CoA reductase
  • EC 1.3.1.53: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase
  • EC 1.3.1.54: precorrin-6A reductase
  • EC 1.3.1.55: now *EC 1.3.1.25
  • EC 1.3.1.56: cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
  • EC 1.3.1.57: phloroglucinol reductase
  • EC 1.3.1.58: 2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase
  • EC 1.3.1.59: 1,2-dihydroxy-3-methyl-1,2-dihydrobenzoate dehydrogenase
  • EC 1.3.1.60: dibenzothiophene dihydrodiol dehydrogenase
  • EC 1.3.1.61: terephthalate 1,2-cis-dihydrodiol dehydrogenase
  • EC 1.3.1.62: pimeloyl-CoA dehydrogenase
  • EC 1.3.1.63: 2,4-dichlorobenzoyl-CoA reductase
  • EC 1.3.1.64: phthalate 4,5-cis-dihydrodiol dehydrogenase
  • EC 1.3.1.65: 5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase
  • EC 1.3.1.66: cis-dihydroethylcatechol dehydrogenase
  • EC 1.3.1.67: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase
  • EC 1.3.1.68: 1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase
  • EC 1.3.1.69: zeatin reductase
  • EC 1.3.1.70: D14-sterol reductase
  • EC 1.3.1.71: D24(241)-sterol reductase
  • EC 1.3.1.72: D24-sterol reductase
  • EC 1.3.1.73: 1,2-dihydrovomilenine reductase
  • EC 1.3.1.74: 2-alkenal reductase
  • EC 1.3.1.75: divinyl chlorophyllide a 8-vinyl-reductase
  • EC 1.3.1.76: precorrin-2 dehydrogenase
  • EC 1.3.1.77: anthocyanidin reductase
  • EC 1.3.1.78: arogenate dehydrogenase (NADP+)
  • EC 1.3.1.79: arogenate dehydrogenase (NAD(P)+)

EC 1.3.2 With a cytochrome as acceptor

  • EC 1.3.2.1: now EC 1.3.99.2
  • EC 1.3.2.2: now EC 1.3.99.3
  • EC 1.3.2.3: galactonolactone dehydrogenase

EC 1.3.3 With oxygen as acceptor

  • EC 1.3.3.1: dihydroorotate oxidase
  • EC 1.3.3.2: lathosterol oxidase
  • EC 1.3.3.3: coproporphyrinogen oxidase
  • EC 1.3.3.4: protoporphyrinogen oxidase
  • EC 1.3.3.5: bilirubin oxidase
  • EC 1.3.3.6: acyl-CoA oxidase
  • EC 1.3.3.7: dihydrouracil oxidase
  • EC 1.3.3.8: tetrahydroberberine oxidase
  • EC 1.3.3.9: secologanin synthase
  • EC 1.3.3.10: tryptophan a,b-oxidase
  • EC 1.3.3.11: pyrroloquinoline-quinone synthase

EC 1.3.5 With a quinone or related compound as acceptor

EC 1.3.7 With an iron-sulfur protein as acceptor

  • EC 1.3.7.1: 6-hydroxynicotinate reductase
  • EC 1.3.7.2: 15,16-dihydrobiliverdin:ferredoxin oxidoreductase
  • EC 1.3.7.3: phycoerythrobilin:ferredoxin oxidoreductase
  • EC 1.3.7.4: phytochromobilin:ferredoxin oxidoreductase
  • EC 1.3.7.5: phycocyanobilin:ferredoxin oxidoreductase

EC 1.3.99 With other acceptors

  • EC 1.3.99.1: succinate dehydrogenase
  • EC 1.3.99.2: butyryl-CoA dehydrogenase
  • EC 1.3.99.3: acyl-CoA dehydrogenase
  • EC 1.3.99.4: 3-oxosteroid 1-dehydrogenase
  • EC 1.3.99.5: 3-oxo-5a-steroid 4-dehydrogenase
  • EC 1.3.99.6: 3-oxo-5b-steroid 4-dehydrogenase
  • EC 1.3.99.7: glutaryl-CoA dehydrogenase
  • EC 1.3.99.8: 2-furoyl-CoA dehydrogenase
  • EC 1.3.99.9: now *EC 1.21.99.1
  • EC 1.3.99.10: isovaleryl-CoA dehydrogenase
  • EC 1.3.99.11: dihydroorotate dehydrogenase
  • EC 1.3.99.12: 2-methylacyl-CoA dehydrogenase
  • EC 1.3.99.13: long-chain-acyl-CoA dehydrogenase
  • EC 1.3.99.14: cyclohexanone dehydrogenase
  • EC 1.3.99.15: benzoyl-CoA reductase
  • EC 1.3.99.16: isoquinoline 1-oxidoreductase
  • EC 1.3.99.17: quinoline 2-oxidoreductase
  • EC 1.3.99.18: quinaldate 4-oxidoreductase
  • EC 1.3.99.19: quinoline-4-carboxylate 2-oxidoreductase
  • EC 1.3.99.20: 4-hydroxybenzoyl-CoA reductase
  • EC 1.3.99.21: (R)-benzylsuccinyl-CoA dehydrogenase
  • EC 1.3.99.22: coproporphyrinogen dehydrogenase

EC 1.4 Acting on the CH-NH2 group of donors

EC 1.4.1 With NAD or NADP as acceptor

  • EC 1.4.1.1: alanine dehydrogenase
  • EC 1.4.1.2: glutamate dehydrogenase
  • EC 1.4.1.3: glutamate dehydrogenase (NAD(P)+)
  • EC 1.4.1.4: glutamate dehydrogenase (NADP+)
  • EC 1.4.1.5: L-amino-acid dehydrogenase
  • EC 1.4.1.6: deleted, included in *EC 1.4.4.1
  • EC 1.4.1.7: serine 2-dehydrogenase
  • EC 1.4.1.8: valine dehydrogenase (NADP+)
  • EC 1.4.1.9: leucine dehydrogenase
  • EC 1.4.1.10: glycine dehydrogenase
  • EC 1.4.1.11: L-erythro-3,5-diaminohexanoate dehydrogenase
  • EC 1.4.1.12: 2,4-diaminopentanoate dehydrogenase
  • EC 1.4.1.13: glutamate synthase (NADPH)
  • EC 1.4.1.14: glutamate synthase (NADH)
  • EC 1.4.1.15: lysine dehydrogenase
  • EC 1.4.1.16: diaminopimelate dehydrogenase
  • EC 1.4.1.17: N-methylalanine dehydrogenase
  • EC 1.4.1.18: lysine 6-dehydrogenase
  • EC 1.4.1.19: tryptophan dehydrogenase
  • EC 1.4.1.20: phenylalanine dehydrogenase
  • EC 1.4.1.21: aspartate dehydrogenase

EC 1.4.2 With a cytochrome as acceptor

  • EC 1.4.2.1: glycine dehydrogenase (cytochrome)

EC 1.4.3 With oxygen as acceptor

  • EC 1.4.3.1: D-aspartate oxidase
  • EC 1.4.3.2: L-amino-acid oxidase
  • EC 1.4.3.3: D-amino-acid oxidase
  • EC 1.4.3.4: amine oxidase (flavin-containing)
  • EC 1.4.3.5: pyridoxamine-phosphate oxidase
  • EC 1.4.3.6: amine oxidase (copper-containing)
  • EC 1.4.3.7: D-glutamate oxidase
  • EC 1.4.3.8: ethanolamine oxidase
  • EC 1.4.3.9: deleted, included in *EC 1.4.3.4
  • EC 1.4.3.10: putrescine oxidase
  • EC 1.4.3.11: L-glutamate oxidase
  • EC 1.4.3.12: cyclohexylamine oxidase
  • EC 1.4.3.13: protein-lysine 6-oxidase
  • EC 1.4.3.14: L-lysine oxidase
  • EC 1.4.3.15: D-glutamate(D-aspartate) oxidase
  • EC 1.4.3.16: L-aspartate oxidase
  • EC 1.4.3.17: now *EC 1.3.3.10
  • EC 1.4.3.18: deleted, not approved
  • EC 1.4.3.19: glycine oxidase

EC 1.4.4 With a disulfide as acceptor

  • EC 1.4.4.1: now EC 1.21.4.1
  • EC 1.4.4.2: glycine dehydrogenase (decarboxylating)

EC 1.4.7 With an iron-sulfur protein as acceptor

  • EC 1.4.7.1: glutamate synthase (ferredoxin)

EC 1.4.99 With other acceptors

  • EC 1.4.99.1: D-amino acid dehydrogenase
  • EC 1.4.99.2: taurine dehydrogenase
  • EC 1.4.99.3: amine dehydrogenase
  • EC 1.4.99.4: aralkylamine dehydrogenase
  • EC 1.4.99.5: glycine dehydrogenase (cyanide-forming)

EC 1.5 Acting on the CH-NH group of donors

EC 1.5.1 With NAD or NADP as acceptor

  • EC 1.5.1.1: pyrroline-2-carboxylate reductase
  • EC 1.5.1.2: pyrroline-5-carboxylate reductase
  • EC 1.5.1.3: dihydrofolate reductase
  • EC 1.5.1.4: deleted, included in *EC 1.5.1.3
  • EC 1.5.1.5: methylenetetrahydrofolate dehydrogenase (NADP+)
  • EC 1.5.1.6: formyltetrahydrofolate dehydrogenase
  • EC 1.5.1.7: saccharopine dehydrogenase (NAD+, L-lysine-forming)
  • EC 1.5.1.8: saccharopine dehydrogenase (NADP+, L-lysine-forming)
  • EC 1.5.1.9: saccharopine dehydrogenase (NAD+, L-glutamate-forming)
  • EC 1.5.1.10: saccharopine dehydrogenase (NADP+, L-glutamate-forming)
  • EC 1.5.1.11: D-octopine dehydrogenase
  • EC 1.5.1.12: 1-pyrroline-5-carboxylate dehydrogenase
  • EC 1.5.1.13: now *EC 1.17.1.5
  • EC 1.5.1.14: deleted, included in *EC 1.5.1.21
  • EC 1.5.1.15: methylenetetrahydrofolate dehydrogenase (NAD+)
  • EC 1.5.1.16: D-lysopine dehydrogenase
  • EC 1.5.1.17: alanopine dehydrogenase
  • EC 1.5.1.18: ephedrine dehydrogenase
  • EC 1.5.1.19: D-nopaline dehydrogenase
  • EC 1.5.1.20: methylenetetrahydrofolate reductase (NAD(P)H)
  • EC 1.5.1.21: D1-piperideine-2-carboxylate reductase
  • EC 1.5.1.22: strombine dehydrogenase
  • EC 1.5.1.23: tauropine dehydrogenase
  • EC 1.5.1.24: N5-(carboxyethyl)ornithine synthase
  • EC 1.5.1.25: thiomorpholine-carboxylate dehydrogenase
  • EC 1.5.1.26: b-alanopine dehydrogenase
  • EC 1.5.1.27: 1,2-dehydroreticulinium reductase (NADPH)
  • EC 1.5.1.28: opine dehydrogenase
  • EC 1.5.1.29: FMN reductase
  • EC 1.5.1.30: flavin reductase
  • EC 1.5.1.31: berberine reductase
  • EC 1.5.1.32: vomilenine reductase
  • EC 1.5.1.33: pteridine reductase
  • EC 1.5.1.34: 6,7-dihydropteridine reductase

EC 1.5.3 With oxygen as acceptor

  • EC 1.5.3.1: sarcosine oxidase
  • EC 1.5.3.2: N-methyl-L-amino-acid oxidase
  • EC 1.5.3.3: deleted
  • EC 1.5.3.4: N6-methyl-lysine oxidase
  • EC 1.5.3.5: (S)-6-hydroxynicotine oxidase
  • EC 1.5.3.6: (R)-6-hydroxynicotine oxidase
  • EC 1.5.3.7: L-pipecolate oxidase
  • EC 1.5.3.8: deleted, included in *EC 1.3.3.8
  • EC 1.5.3.9: now *EC 1.21.3.3
  • EC 1.5.3.10: dimethylglycine oxidase
  • EC 1.5.3.11: polyamine oxidase
  • EC 1.5.3.12: dihydrobenzophenanthridine oxidase

EC 1.5.4 With a disulfide as acceptor

  • EC 1.5.4.1: pyrimidodiazepine synthase

EC 1.5.5 With a quinone or similar compound as acceptor

  • EC 1.5.5.1: electron-transferring-flavoprotein dehydrogenase

EC 1.5.7 With an iron-sulfur protein as acceptor

  • EC 1.5.7.1: methylenetetrahydrofolate reductase (ferredoxin)

EC 1.5.8 With a flavin as acceptor

  • EC 1.5.8.1: dimethylamine dehydrogenase
  • EC 1.5.8.2: trimethylamine dehydrogenase

EC 1.5.99 With other acceptors

  • EC 1.5.99.1: sarcosine dehydrogenase
  • EC 1.5.99.2: dimethylglycine dehydrogenase
  • EC 1.5.99.3: L-pipecolate dehydrogenase
  • EC 1.5.99.4: nicotine dehydrogenase
  • EC 1.5.99.5: methylglutamate dehydrogenase
  • EC 1.5.99.6: spermidine dehydrogenase
  • EC 1.5.99.7: now *EC 1.5.8.2
  • EC 1.5.99.8: proline dehydrogenase
  • EC 1.5.99.9: methylenetetrahydromethanopterin dehydrogenase
  • EC 1.5.99.10: now *EC 1.5.8.1
  • EC 1.5.99.11: 5,10-methylenetetrahydromethanopterin reductase
  • EC 1.5.99.12: cytokinin dehydrogenase

EC 1.6 Acting on NADH or NADPH

EC 1.6.1 With NAD or NADP as acceptor

  • EC 1.6.1.1: NAD(P)+ transhydrogenase (B-specific)
  • EC 1.6.1.2: NAD(P)+ transhydrogenase (AB-specific)

EC 1.6.2 With a heme protein as acceptor

  • EC 1.6.2.1: now EC 1.6.99.3
  • EC 1.6.2.2: cytochrome-b5 reductase
  • EC 1.6.2.3: deleted
  • EC 1.6.2.4: NADPH—hemoprotein reductase
  • EC 1.6.2.5: NADPH—cytochrome-c2 reductase
  • EC 1.6.2.6: leghemoglobin reductase

EC 1.6.3 With oxygen as acceptor

  • EC 1.6.3.1: NAD(P)H oxidase

EC 1.6.4 With a disulfide as acceptor

  • EC 1.6.4.1: now EC 1.8.1.6
  • EC 1.6.4.2: now EC 1.8.1.7
  • EC 1.6.4.3: now EC 1.8.1.4
  • EC 1.6.4.4: now EC 1.8.1.8
  • EC 1.6.4.5: now EC 1.8.1.9
  • EC 1.6.4.6: now EC 1.8.1.10
  • EC 1.6.4.7: now EC 1.8.1.11
  • EC 1.6.4.8: now EC 1.8.1.12
  • EC 1.6.4.9: now EC 1.8.1.13
  • EC 1.6.4.10: now EC 1.8.1.14

EC 1.6.5 With a quinone or similar compound as acceptor

  • EC 1.6.5.1: deleted
  • EC 1.6.5.2: NAD(P)H dehydrogenase (quinone)
  • EC 1.6.5.3: NADH dehydrogenase (ubiquinone)
  • EC 1.6.5.4: monodehydroascorbate reductase (NADH)
  • EC 1.6.5.5: NADPH:quinone reductase
  • EC 1.6.5.6: p-benzoquinone reductase (NADPH)
  • EC 1.6.5.7: 2-hydroxy-1,4-benzoquinone reductase

EC 1.6.6 With a nitrogenous group as acceptor

  • EC 1.6.6.1: now *EC 1.7.1.1
  • EC 1.6.6.2: now *EC 1.7.1.2
  • EC 1.6.6.3: now *EC 1.7.1.3
  • EC 1.6.6.4: now *EC 1.7.1.4
  • EC 1.6.6.5: now *EC 1.7.99.3
  • EC 1.6.6.6: now *EC 1.7.1.5
  • EC 1.6.6.7: now *EC 1.7.1.6
  • EC 1.6.6.8: now *EC 1.7.1.7
  • EC 1.6.6.9: trimethylamine-N-oxide reductase
  • EC 1.6.6.10: now *EC 1.7.1.9
  • EC 1.6.6.11: now *EC 1.7.1.10
  • EC 1.6.6.12: now *EC 1.7.1.11
  • EC 1.6.6.13: now *EC 1.7.1.12

EC 1.6.7 With an iron-sulfur protein as acceptor

  • EC 1.6.7.1: now EC 1.18.1.2
  • EC 1.6.7.2: now EC 1.18.1.1

EC 1.6.8 With a flavin as acceptor

  • EC 1.6.8.1: now EC 1.5.1.29
  • EC 1.6.8.2: now EC 1.5.1.30

EC 1.6.99 With other acceptors

  • EC 1.6.99.1: NADPH dehydrogenase
  • EC 1.6.99.2: now *EC 1.6.5.2
  • EC 1.6.99.3: NADH dehydrogenase
  • EC 1.6.99.4: now *EC 1.18.1.2
  • EC 1.6.99.5: NADH dehydrogenase (quinone)
  • EC 1.6.99.6: NADPH dehydrogenase (quinone)
  • EC 1.6.99.7: now *EC 1.5.1.34
  • EC 1.6.99.8: now *EC 1.16.1.3
  • EC 1.6.99.9: now *EC 1.16.1.4
  • EC 1.6.99.10: deleted, included in *EC 1.6.99.7
  • EC 1.6.99.11: now *EC 1.16.1.5
  • EC 1.6.99.12: now *EC 1.16.1.6
  • EC 1.6.99.13: now *EC 1.16.1.7

EC 1.7 Acting on other nitrogenous compounds as donors

EC 1.7.1 With NAD+ or NADP+ as acceptor

  • EC 1.7.1.1: nitrate reductase (NADH)
  • EC 1.7.1.2: nitrate reductase (NAD(P)H)
  • EC 1.7.1.3: nitrate reductase (NADPH)
  • EC 1.7.1.4: nitrite reductase (NAD(P)H)
  • EC 1.7.1.5: hyponitrite reductase
  • EC 1.7.1.6: azobenzene reductase
  • EC 1.7.1.7: GMP reductase
  • EC 1.7.1.8: deleted entry
  • EC 1.7.1.9: nitroquinoline-N-oxide reductase
  • EC 1.7.1.10: hydroxylamine reductase (NADH)
  • EC 1.7.1.11: 4-(dimethylamino)phenylazoxybenzene reductase
  • EC 1.7.1.12: N-hydroxy-2-acetamidofluorene reductase

EC 1.7.2 With a cytochrome as acceptor

  • EC 1.7.2.1: nitrite reductase (NO-forming)
  • EC 1.7.2.2: nitrite reductase (cytochrome; ammonia-forming)
  • EC 1.7.2.3: trimethylamine-N-oxide reductase (cytochrome c)

EC 1.7.3 With oxygen as acceptor

  • EC 1.7.3.1: nitroalkane oxidase
  • EC 1.7.3.2: acetylindoxyl oxidase
  • EC 1.7.3.3: urate oxidase
  • EC 1.7.3.4: hydroxylamine oxidase
  • EC 1.7.3.5: 3-aci-nitropropanoate oxidase

EC 1.7.7 With an iron-sulfur protein as acceptor

  • EC 1.7.7.1: ferredoxin—nitrite reductase
  • EC 1.7.7.2: ferredoxin—nitrate reductase

EC 1.7.99 With other acceptors

  • EC 1.7.99.1: hydroxylamine reductase
  • EC 1.7.99.2: deleted
  • EC 1.7.99.3: included with *EC 1.7.2.1
  • EC 1.7.99.4: nitrate reductase
  • EC 1.7.99.5: deleted, now included with *EC 1.5.1.20
  • EC 1.7.99.6: nitrous-oxide reductase
  • EC 1.7.99.7: nitric-oxide reductase
  • EC 1.7.99.8: hydroxylamine oxidoreductase

EC 1.8 Acting on a sulfur group of donors

EC 1.8.1 With NAD or NADP as acceptor

  • EC 1.8.1.1: deleted
  • EC 1.8.1.2: sulfite reductase (NADPH)
  • EC 1.8.1.3: hypotaurine dehydrogenase
  • EC 1.8.1.4: dihydrolipoyl dehydrogenase
  • EC 1.8.1.5: 2-oxopropyl-CoM reductase (carboxylating)
  • EC 1.8.1.6: cystine reductase
  • EC 1.8.1.7: glutathione-disulfide reductase
  • EC 1.8.1.8: protein-disulfide reductase
  • EC 1.8.1.9: thioredoxin-disulfide reductase
  • EC 1.8.1.10: CoA-glutathione reductase
  • EC 1.8.1.11: asparagusate reductase
  • EC 1.8.1.12: trypanothione-disulfide reductase
  • EC 1.8.1.13: bis-g-glutamylcystine reductase
  • EC 1.8.1.14: CoA-disulfide reductase
  • EC 1.8.1.15: mycothione reductase

EC 1.8.2 With a cytochrome as acceptor

  • EC 1.8.2.1: sulfite dehydrogenase
  • EC 1.8.2.2: thiosulfate dehydrogenase

EC 1.8.3 With oxygen as acceptor

  • EC 1.8.3.1: sulfite oxidase
  • EC 1.8.3.2: thiol oxidase
  • EC 1.8.3.3: glutathione oxidase
  • EC 1.8.3.4: methanethiol oxidase
  • EC 1.8.3.5: prenylcysteine oxidase

EC 1.8.4 With a disulfide as acceptor

  • EC 1.8.4.1: glutathione—homocystine transhydrogenase
  • EC 1.8.4.2: protein-disulfide reductase (glutathione)
  • EC 1.8.4.3: glutathione—CoA-glutathione transhydrogenase
  • EC 1.8.4.4: glutathione—cystine transhydrogenase
  • EC 1.8.4.5: methionine-S-oxide reductase
  • EC 1.8.4.6: protein-methionine-S-oxide reductase
  • EC 1.8.4.7: enzyme-thiol transhydrogenase (glutathione-disulfide)
  • EC 1.8.4.8: phosphoadenylyl-sulfate reductase (thioredoxin)
  • EC 1.8.4.9: adenylyl-sulfate reductase (glutathione)
  • EC 1.8.4.10: adenylyl-sulfate reductase (thioredoxin)

EC 1.8.5 With a quinone or similar compound as acceptor

  • EC 1.8.5.1: glutathione dehydrogenase (ascorbate)
  • EC 1.8.5.2: thiosulfate dehydrogenase (quinone)

EC 1.8.6 With a nitrogenous group as acceptor

  • EC 1.8.6.1: deleted, included in EC 2.5.1.18

EC 1.8.7 With an iron-sulfur protein as acceptor

EC 1.8.98 With other, known, acceptors

  • EC 1.8.98.1: CoB—CoM heterodisulfide reductase
  • EC 1.8.98.2: sulfiredoxin

EC 1.8.99 With other acceptors

  • EC 1.8.99.1: sulfite reductase
  • EC 1.8.99.2: adenylyl-sulfate reductase
  • EC 1.8.99.3: hydrogensulfite reductase
  • EC 1.8.99.4: now EC 1.8.4.8

EC 1.9 Acting on a heme group of donors

EC 1.9.3 With oxygen as acceptor

EC 1.9.6 With a nitrogenous group as acceptor

  • EC 1.9.6.1: nitrate reductase (cytochrome)

EC 1.9.99 With other acceptors

  • EC 1.9.99.1: iron—cytochrome-c reductase

EC 1.10 Acting on diphenols and related substances as donors

EC 1.10.1 With NAD or NADP as acceptor

  • EC 1.10.1.1: trans-acenaphthene-1,2-diol dehydrogenase

EC 1.10.2 With a cytochrome as acceptor

EC 1.10.3 With oxygen as acceptor

  • EC 1.10.3.1: catechol oxidase
  • EC 1.10.3.2: laccase
  • EC 1.10.3.3: L-ascorbate oxidase
  • EC 1.10.3.4: o-aminophenol oxidase
  • EC 1.10.3.5: 3-hydroxyanthranilate oxidase
  • EC 1.10.3.6: rifamycin-B oxidase
  • EC 1.10.3.7: now *EC 1.21.3.4
  • EC 1.10.3.8: now *EC 1.21.3.5

EC 1.10.99 With other acceptors

EC 1.11 Acting on a peroxide as acceptor

EC 1.11.1 Peroxidases

  • EC 1.11.1.1: NADH peroxidase
  • EC 1.11.1.2: NADPH peroxidase
  • EC 1.11.1.3: fatty-acid peroxidase
  • EC 1.11.1.4: now *EC 1.13.11.11
  • EC 1.11.1.5: cytochrome-c peroxidase
  • EC 1.11.1.6: catalase
  • EC 1.11.1.7: peroxidase
  • EC 1.11.1.8: iodide peroxidase
  • EC 1.11.1.9: glutathione peroxidase
  • EC 1.11.1.10: chloride peroxidase
  • EC 1.11.1.11: L-ascorbate peroxidase
  • EC 1.11.1.12: phospholipid-hydroperoxide glutathione peroxidase
  • EC 1.11.1.13: manganese peroxidase
  • EC 1.11.1.14: diarylpropane peroxidase
  • EC 1.11.1.15: peroxiredoxin

EC 1.12 Acting on hydrogen as donor

EC 1.12.1 With NAD or NADP as acceptor

  • EC 1.12.1.1: now EC 1.18.99.1
  • EC 1.12.1.2: hydrogen dehydrogenase
  • EC 1.12.1.3: hydrogen dehydrogenase (NADP+)

EC 1.12.2 With a cytochrome as acceptor

  • EC 1.12.2.1: cytochrome-c3 hydrogenase

EC 1.12.5 With a quinone or similar compound as acceptor

  • EC 1.12.5.1: hydrogen:quinone oxidoreductase

EC 1.12.7 With an iron-sulfur protein as acceptor

  • EC 1.12.7.1: now EC 1.18.99.1
  • EC 1.12.7.2: ferredoxin hydrogenase

EC 1.12.98 With other known acceptors

  • EC 1.12.98.1: coenzyme F420 hydrogenase
  • EC 1.12.98.2: 5,10-methenyltetrahydromethanopterin hydrogenase
  • EC 1.12.98.3: Methanosarcina-phenazine hydrogenase

EC 1.12.99 With other acceptors

  • EC 1.12.99.1: now *EC 1.12.98.1
  • EC 1.12.99.2: deleted, composed of *EC 1.12.98.3 and *EC 1.8.98.1
  • EC 1.12.99.3: now *EC 1.12.5.1
  • EC 1.12.99.4: now *EC 1.12.98.2
  • EC 1.12.99.5: identical to *EC 1.13.11.47
  • EC 1.12.99.6: hydrogenase (acceptor)

EC 1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)

EC 1.13.1 (transferred to EC 1.13.11)

  • EC 1.13.1.1: now *EC 1.13.11.1
  • EC 1.13.1.2: now *EC 1.13.11.2
  • EC 1.13.1.3: now *EC 1.13.11.3
  • EC 1.13.1.4: now *EC 1.13.11.4
  • EC 1.13.1.5: now *EC 1.13.11.5
  • EC 1.13.1.6: now *EC 1.13.11.6
  • EC 1.13.1.7: now *EC 1.13.11.7
  • EC 1.13.1.8: now *EC 1.13.11.8
  • EC 1.13.1.9: now *EC 1.13.11.9
  • EC 1.13.1.10: now *EC 1.13.11.10
  • EC 1.13.1.11: now *EC 1.13.99.1
  • EC 1.13.1.12: now *EC 1.13.11.11
  • EC 1.13.1.13: now *EC 1.13.11.12

EC 1.13.11 With incorporation of two atoms of oxygen

  • EC 1.13.11.1: catechol 1,2-dioxygenase
  • EC 1.13.11.2: catechol 2,3-dioxygenase
  • EC 1.13.11.3: protocatechuate 3,4-dioxygenase
  • EC 1.13.11.4: gentisate 1,2-dioxygenase
  • EC 1.13.11.5: homogentisate 1,2-dioxygenase
  • EC 1.13.11.6: 3-hydroxyanthranilate 3,4-dioxygenase
  • EC 1.13.11.7: deleted
  • EC 1.13.11.8: protocatechuate 4,5-dioxygenase
  • EC 1.13.11.9: 2,5-dihydroxypyridine 5,6-dioxygenase
  • EC 1.13.11.10: 7,8-dihydroxykynurenate 8,8a-dioxygenase
  • EC 1.13.11.11: tryptophan 2,3-dioxygenase
  • EC 1.13.11.12: lipoxygenase
  • EC 1.13.11.13: ascorbate 2,3-dioxygenase
  • EC 1.13.11.14: 2,3-dihydroxybenzoate 3,4-dioxygenase
  • EC 1.13.11.15: 3,4-dihydroxyphenylacetate 2,3-dioxygenase
  • EC 1.13.11.16: 3-carboxyethylcatechol 2,3-dioxygenase
  • EC 1.13.11.17: indole 2,3-dioxygenase
  • EC 1.13.11.18: sulfur dioxygenase
  • EC 1.13.11.19: cysteamine dioxygenase
  • EC 1.13.11.20: cysteine dioxygenase
  • EC 1.13.11.21: now *EC 1.14.99.36
  • EC 1.13.11.22: caffeate 3,4-dioxygenase
  • EC 1.13.11.23: 2,3-dihydroxyindole 2,3-dioxygenase
  • EC 1.13.11.24: quercetin 2,3-dioxygenase
  • EC 1.13.11.25: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase
  • EC 1.13.11.26: peptide-tryptophan 2,3-dioxygenase
  • EC 1.13.11.27: 4-hydroxyphenylpyruvate dioxygenase
  • EC 1.13.11.28: 2,3-dihydroxybenzoate 2,3-dioxygenase
  • EC 1.13.11.29: stizolobate synthase
  • EC 1.13.11.30: stizolobinate synthase
  • EC 1.13.11.31: arachidonate 12-lipoxygenase
  • EC 1.13.11.32: 2-nitropropane dioxygenase
  • EC 1.13.11.33: arachidonate 15-lipoxygenase
  • EC 1.13.11.34: arachidonate 5-lipoxygenase
  • EC 1.13.11.35: pyrogallol 1,2-oxygenase
  • EC 1.13.11.36: chloridazon-catechol dioxygenase
  • EC 1.13.11.37: hydroxyquinol 1,2-dioxygenase
  • EC 1.13.11.38: 1-hydroxy-2-naphthoate 1,2-dioxygenase
  • EC 1.13.11.39: biphenyl-2,3-diol 1,2-dioxygenase
  • EC 1.13.11.40: arachidonate 8-lipoxygenase
  • EC 1.13.11.41: 2,4'-dihydroxyacetophenone dioxygenase
  • EC 1.13.11.42: indoleamine-pyrrole 2,3-dioxygenase
  • EC 1.13.11.43: lignostilbene ab-dioxygenase
  • EC 1.13.11.44: linoleate diol synthase
  • EC 1.13.11.45: linoleate 11-lipoxygenase
  • EC 1.13.11.46: 4-hydroxymandelate synthase
  • EC 1.13.11.47: 3-hydroxy-4-oxoquinoline 2,4-dioxygenase
  • EC 1.13.11.48: 3-hydroxy-2-methyl-quinolin-4-one 2,4-dioxygenase
  • EC 1.13.11.49: chlorite O2-lyase
  • EC 1.13.11.50: acetylacetone-cleaving enzyme

EC 1.13.12 With incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)

  • EC 1.13.12.1: arginine 2-monooxygenase
  • EC 1.13.12.2: lysine 2-monooxygenase
  • EC 1.13.12.3: tryptophan 2-monooxygenase
  • EC 1.13.12.4: lactate 2-monooxygenase
  • EC 1.13.12.5: Renilla-luciferin 2-monooxygenase
  • EC 1.13.12.6: Cypridina-luciferin 2-monooxygenase
  • EC 1.13.12.7: Photinus-luciferin 4-monooxygenase (ATP-hydrolysing)
  • EC 1.13.12.8: Watasenia-luciferin 2-monooxygenase
  • EC 1.13.12.9: phenylalanine 2-monooxygenase
  • EC 1.13.12.10: covered by *EC 1.14.13.59
  • EC 1.13.12.11: methylphenyltetrahydropyridine N-monooxygenase
  • EC 1.13.12.12: apo-b-carotenoid-14',13'-dioxygenase
  • EC 1.13.12.13: Oplophorus-luciferin 2-monooxygenase

EC 1.13.99 Miscellaneous

  • EC 1.13.99.1: inositol oxygenase
  • EC 1.13.99.2: now EC 1.14.12.10
  • EC 1.13.99.3: tryptophan 2'-dioxygenase
  • EC 1.13.99.4: now EC 1.14.12.9
  • EC 1.13.99.5: now EC 1.13.11.47

EC 1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen

EC 1.14.1 With NADH or NADPH as one donor (deleted sub-subclass)

  • EC 1.14.1.1: now *EC 1.14.14.1
  • EC 1.14.1.2: now *EC 1.14.13.9
  • EC 1.14.1.3: deleted, covered by *EC 1.14.99.7, *EC 5.4.99.7
  • EC 1.14.1.4: now *EC 1.14.99.2
  • EC 1.14.1.5: now *EC 1.14.13.5
  • EC 1.14.1.6: now *EC 1.14.15.4
  • EC 1.14.1.7: now *EC 1.14.99.9
  • EC 1.14.1.8: now *EC 1.14.99.10
  • EC 1.14.1.9: deleted
  • EC 1.14.1.10: now *EC 1.14.99.11
  • EC 1.14.1.11: deleted

EC 1.14.2 With ascorbate as one donor (deleted sub-subclass)

  • EC 1.14.2.1: now EC 1.14.17.1
  • EC 1.14.2.2: now EC 1.13.11.27

EC 1.14.3 With reduced pteridine as one donor (deleted sub-subclass)

  • EC 1.14.3.1: now EC 1.14.16.1

EC 1.14.11 With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors

  • EC 1.14.11.1: g-butyrobetaine dioxygenase
  • EC 1.14.11.2: procollagen-proline dioxygenase
  • EC 1.14.11.3: pyrimidine-deoxynucleoside 2'-dioxygenase
  • EC 1.14.11.4: procollagen-lysine 5-dioxygenase
  • EC 1.14.11.5: deleted, included in *EC 1.14.11.6
  • EC 1.14.11.6: thymine dioxygenase
  • EC 1.14.11.7: procollagen-proline 3-dioxygenase
  • EC 1.14.11.8: trimethyllysine dioxygenase
  • EC 1.14.11.9: flavanone 3-dioxygenase
  • EC 1.14.11.10: pyrimidine-deoxynucleoside 1'-dioxygenase
  • EC 1.14.11.11: hyoscyamine (6S)-dioxygenase
  • EC 1.14.11.12: gibberellin-44 dioxygenase
  • EC 1.14.11.13: gibberellin 2b-dioxygenase
  • EC 1.14.11.14: 6b-hydroxyhyoscyamine epoxidase
  • EC 1.14.11.15: gibberellin 3b-dioxygenase
  • EC 1.14.11.16: peptide-aspartate b-dioxygenase
  • EC 1.14.11.17: taurine dioxygenase
  • EC 1.14.11.18: phytanoyl-CoA dioxygenase
  • EC 1.14.11.19: leucocyanidin oxygenase
  • EC 1.14.11.20: deacetoxyvindoline 4-hydroxylase
  • EC 1.14.11.21: clavaminate synthase
  • EC 1.14.11.22: flavone synthase
  • EC 1.14.11.23: flavonol synthase
  • EC 1.14.11.24: 2'-deoxymugineic-acid 2'-dioxygenase
  • EC 1.14.11.25: mugineic-acid 3-dioxygenase

EC 1.14.12 With NADH or NADPH as one donor, and incorporation of two atoms of oxygen into one donor

  • EC 1.14.12.1: anthranilate 1,2-dioxygenase (deaminating, decarboxylating)
  • EC 1.14.12.2: now *EC 1.14.13.35
  • EC 1.14.12.3: benzene 1,2-dioxygenase
  • EC 1.14.12.4: 3-hydroxy-2-methylpyridinecarboxylate dioxygenase
  • EC 1.14.12.5: 5-pyridoxate dioxygenase
  • EC 1.14.12.6: now *EC 1.14.13.66
  • EC 1.14.12.7: phthalate 4,5-dioxygenase
  • EC 1.14.12.8: 4-sulfobenzoate 3,4-dioxygenase
  • EC 1.14.12.9: 4-chlorophenylacetate 3,4-dioxygenase
  • EC 1.14.12.10: benzoate 1,2-dioxygenase
  • EC 1.14.12.11: toluene dioxygenase
  • EC 1.14.12.12: naphthalene 1,2-dioxygenase
  • EC 1.14.12.13: 2-chlorobenzoate 1,2-dioxygenase
  • EC 1.14.12.14: 2-aminobenzenesulfonate 2,3-dioxygenase
  • EC 1.14.12.15: terephthalate 1,2-dioxygenase
  • EC 1.14.12.16: 2-hydroxyquinoline 5,6-dioxygenase
  • EC 1.14.12.17: nitric oxide dioxygenase
  • EC 1.14.12.18: biphenyl 2,3-dioxygenase
  • EC 1.14.12.19: 3-phenylpropionate dioxygenase

EC 1.14.13 With NADH or NADPH as one donor, and incorporation of one atom of oxygen

  • EC 1.14.13.1: salicylate 1-monooxygenase
  • EC 1.14.13.2: 4-hydroxybenzoate 3-monooxygenase
  • EC 1.14.13.3: 4-hydroxyphenylacetate 3-monooxygenase
  • EC 1.14.13.4: melilotate 3-monooxygenase
  • EC 1.14.13.5: imidazoleacetate 4-monooxygenase
  • EC 1.14.13.6: orcinol 2-monooxygenase
  • EC 1.14.13.7: phenol 2-monooxygenase
  • EC 1.14.13.8: dimethylaniline monooxygenase (N-oxide-forming)
  • EC 1.14.13.9: kynurenine 3-monooxygenase
  • EC 1.14.13.10: 2,6-dihydroxypyridine 3-monooxygenase
  • EC 1.14.13.11: trans-cinnamate 4-monooxygenase
  • EC 1.14.13.12: benzoate 4-monooxygenase
  • EC 1.14.13.13: calcidiol 1-monooxygenase
  • EC 1.14.13.14: trans-cinnamate 2-monooxygenase
  • EC 1.14.13.15: cholestanetriol 26-monooxygenase
  • EC 1.14.13.16: cyclopentanone monooxygenase
  • EC 1.14.13.17: cholesterol 7a-monooxygenase
  • EC 1.14.13.18: 4-hydroxyphenylacetate 1-monooxygenase
  • EC 1.14.13.19: taxifolin 8-monooxygenase
  • EC 1.14.13.20: 2,4-dichlorophenol 6-monooxygenase
  • EC 1.14.13.21: flavonoid 3'-monooxygenase
  • EC 1.14.13.22: cyclohexanone monooxygenase
  • EC 1.14.13.23: 3-hydroxybenzoate 4-monooxygenase
  • EC 1.14.13.24: 3-hydroxybenzoate 6-monooxygenase
  • EC 1.14.13.25: methane monooxygenase
  • EC 1.14.13.26: phosphatidylcholine 12-monooxygenase
  • EC 1.14.13.27: 4-aminobenzoate 1-monooxygenase
  • EC 1.14.13.28: 3,9-dihydroxypterocarpan 6a-monooxygenase
  • EC 1.14.13.29: 4-nitrophenol 2-monooxygenase
  • EC 1.14.13.30: leukotriene-B4 20-monooxygenase
  • EC 1.14.13.31: 2-nitrophenol 2-monooxygenase
  • EC 1.14.13.32: albendazole monooxygenase
  • EC 1.14.13.33: 4-hydroxybenzoate 3-monooxygenase (NAD(P)H)
  • EC 1.14.13.34: leukotriene-E4 20-monooxygenase
  • EC 1.14.13.35: anthranilate 3-monooxygenase (deaminating)
  • EC 1.14.13.36: 5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase
  • EC 1.14.13.37: methyltetrahydroprotoberberine 14-monooxygenase
  • EC 1.14.13.38: anhydrotetracycline monooxygenase
  • EC 1.14.13.39: nitric-oxide synthase
  • EC 1.14.13.40: anthraniloyl-CoA monooxygenase
  • EC 1.14.13.41: tyrosine N-monooxygenase
  • EC 1.14.13.42: hydroxyphenylacetonitrile 2-monooxygenase
  • EC 1.14.13.43: questin monooxygenase
  • EC 1.14.13.44: 2-hydroxybiphenyl 3-monooxygenase
  • EC 1.14.13.45: now *EC 1.14.18.2
  • EC 1.14.13.46: (-)-menthol monooxygenase
  • EC 1.14.13.47: (S)-limonene 3-monooxygenase
  • EC 1.14.13.48: (S)-limonene 6-monooxygenase
  • EC 1.14.13.49: (S)-limonene 7-monooxygenase
  • EC 1.14.13.50: pentachlorophenol monooxygenase
  • EC 1.14.13.51: 6-oxocineole dehydrogenase
  • EC 1.14.13.52: isoflavone 3'-hydroxylase
  • EC 1.14.13.53: 4'-methoxyisoflavone 2'-hydroxylase
  • EC 1.14.13.54: ketosteroid monooxygenase
  • EC 1.14.13.55: protopine 6-monooxygenase
  • EC 1.14.13.56: dihydrosanguinarine 10-monooxygenase
  • EC 1.14.13.57: dihydrochelirubine 12-monooxygenase
  • EC 1.14.13.58: benzoyl-CoA 3-monooxygenase
  • EC 1.14.13.59: L-lysine 6-monooxygenase (NADPH)
  • EC 1.14.13.60: 27-hydroxycholesterol 7a-monooxygenase
  • EC 1.14.13.61: 2-hydroxyquinoline 8-monooxygenase
  • EC 1.14.13.62: 4-hydroxyquinoline 3-monooxygenase
  • EC 1.14.13.63: 3-hydroxyphenylacetate 6-hydroxylase
  • EC 1.14.13.64: 4-hydroxybenzoate 1-hydroxylase
  • EC 1.14.13.65: 2-hydroxyquinoline 8-monooxygenase
  • EC 1.14.13.66: 2-hydroxycyclohexanone 2-monooxygenase
  • EC 1.14.13.67: quinine 3-monooxygenase
  • EC 1.14.13.68: 4-hydroxyphenylacetaldehyde oxime monooxygenase
  • EC 1.14.13.69: alkene monooxygenase
  • EC 1.14.13.70: sterol 14-demethylase
  • EC 1.14.13.71: N-methylcoclaurine 3'-monooxygenase
  • EC 1.14.13.72: methylsterol monooxygenase
  • EC 1.14.13.73: tabersonine 16-hydroxylase
  • EC 1.14.13.74: 7-deoxyloganin 7-hydroxylase
  • EC 1.14.13.75: vinorine hydroxylase
  • EC 1.14.13.76: taxane 10b-hydroxylase
  • EC 1.14.13.77: taxane 13a-hydroxylase
  • EC 1.14.13.78: ent-kaurene oxidase
  • EC 1.14.13.79: ent-kaurenoic acid oxidase
  • EC 1.14.13.80: (R)-limonene 6-monooxygenase
  • EC 1.14.13.81: magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase
  • EC 1.14.13.82: vanillate monooxygenase
  • EC 1.14.13.83: precorrin-3B synthase
  • EC 1.14.13.84: 4-hydroxyacetophenone monooxygenase
  • EC 1.14.13.85: glyceollin synthase
  • EC 1.14.13.86: 2-hydroxyisoflavanone synthase
  • EC 1.14.13.87: licodione synthase
  • EC 1.14.13.88: flavonoid 3',5'-hydroxylase
  • EC 1.14.13.89: isoflavone 2'-hydroxylase
  • EC 1.14.13.90: zeaxanthin epoxidase
  • EC 1.14.13.91: deoxysarpagine hydroxylase
  • EC 1.14.13.92: phenylacetone monooxygenase

EC 1.14.14 With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen

  • EC 1.14.14.1: unspecific monooxygenase
  • EC 1.14.14.2: deleted, included in EC 1.14.14.1
  • EC 1.14.14.3: alkanal monooxygenase (FMN-linked)
  • EC 1.14.14.4: deleted, identical to EC 1.14.15.7
  • EC 1.14.14.5: alkanesulfonate monooxygenase

EC 1.14.15 With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

  • EC 1.14.15.1: camphor 5-monooxygenase
  • EC 1.14.15.2: camphor 1,2-monooxygenase
  • EC 1.14.15.3: alkane 1-monooxygenase
  • EC 1.14.15.4: steroid 11b-monooxygenase
  • EC 1.14.15.5: corticosterone 18-monooxygenase
  • EC 1.14.15.6: cholesterol monooxygenase (side-chain-cleaving)
  • EC 1.14.15.7: choline monooxygenase

EC 1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen

  • EC 1.14.16.1: phenylalanine 4-monooxygenase
  • EC 1.14.16.2: tyrosine 3-monooxygenase
  • EC 1.14.16.3: anthranilate 3-monooxygenase
  • EC 1.14.16.4: tryptophan 5-monooxygenase
  • EC 1.14.16.5: glyceryl-ether monooxygenase
  • EC 1.14.16.6: mandelate 4-monooxygenase

EC 1.14.17 With reduced ascorbate as one donor, and incorporation of one atom of oxygen

  • EC 1.14.17.1: dopamine b-monooxygenase
  • EC 1.14.17.2: deleted, included in EC 1.14.18.1
  • EC 1.14.17.3: peptidylglycine monooxygenase
  • EC 1.14.17.4: aminocyclopropanecarboxylate oxidase

EC 1.14.18 With another compound as one donor, and incorporation of one atom of oxygen

EC 1.14.19 With oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water

  • EC 1.14.19.1: stearoyl-CoA 9-desaturase
  • EC 1.14.19.2: acyl-(acyl-carrier-protein) desaturase
  • EC 1.14.19.3: linoleoyl-CoA desaturase

EC 1.14.20 With 2-oxoglutarate as one donor, and the other dehydrogenated

  • EC 1.14.20.1: deacetoxycephalosporin-C synthase

EC 1.14.21 With NADH or NADPH as one donor, and the other dehydrogenated

  • EC 1.14.21.1: (S)-stylopine synthase
  • EC 1.14.21.2: (S)-cheilanthifoline synthase
  • EC 1.14.21.3: berbamunine synthase
  • EC 1.14.21.4: salutaridine synthase
  • EC 1.14.21.5: (S)-canadine synthase

EC 1.14.99 Miscellaneous

  • EC 1.14.99.1: prostaglandin-endoperoxide synthase
  • EC 1.14.99.2: kynurenine 7,8-hydroxylase
  • EC 1.14.99.3: heme oxygenase (decyclizing)
  • EC 1.14.99.4: progesterone monooxygenase
  • EC 1.14.99.5: now *EC 1.14.19.1
  • EC 1.14.99.6: now *EC 1.14.19.2
  • EC 1.14.99.7: squalene monooxygenase
  • EC 1.14.99.8: deleted, included in *EC 1.14.14.1
  • EC 1.14.99.9: steroid 17a-monooxygenase
  • EC 1.14.99.10: steroid 21-monooxygenase
  • EC 1.14.99.11: estradiol 6b-monooxygenase
  • EC 1.14.99.12: 4-androstene-3,17-dione monooxygenase
  • EC 1.14.99.13: now *EC 1.14.13.23
  • EC 1.14.99.14: progesterone 11a-monooxygenase
  • EC 1.14.99.15: 4-methoxybenzoate monooxygenase (O-demethylating)
  • EC 1.14.99.16: now *EC 1.14.13.72
  • EC 1.14.99.17: now *EC 1.14.16.5
  • EC 1.14.99.18: deleted
  • EC 1.14.99.19: plasmanylethanolamine desaturase
  • EC 1.14.99.20: phylloquinone monooxygenase (2,3-epoxidizing)
  • EC 1.14.99.21: Latia-luciferin monooxygenase (demethylating)
  • EC 1.14.99.22: ecdysone 20-monooxygenase
  • EC 1.14.99.23: 3-hydroxybenzoate 2-monooxygenase
  • EC 1.14.99.24: steroid 9a-monooxygenase
  • EC 1.14.99.25: now *EC 1.14.19.3
  • EC 1.14.99.26: 2-hydroxypyridine 5-monooxygenase
  • EC 1.14.99.27: juglone 3-monooxygenase
  • EC 1.14.99.28: linalool 8-monooxygenase
  • EC 1.14.99.29: deoxyhypusine monooxygenase
  • EC 1.14.99.30: carotene 7,8-desaturase
  • EC 1.14.99.31: myristoyl-CoA 11-(E) desaturase
  • EC 1.14.99.32: myristoyl-CoA 11-(Z) desaturase
  • EC 1.14.99.33: D12-fatty acid dehydrogenase
  • EC 1.14.99.34: monoprenyl isoflavone epoxidase
  • EC 1.14.99.35: thiophene-2-carbonyl-CoA monooxygenase
  • EC 1.14.99.36: b-carotene 15,15'-monooxygenase
  • EC 1.14.99.37: taxadiene 5a-hydroxylase

EC 1.15 Acting on superoxide as acceptor

EC 1.15.1

EC 1.16 Oxidizing metal ions

EC 1.16.1 With NAD or NADP as acceptor

  • EC 1.16.1.1: mercury(II) reductase
  • EC 1.16.1.2: diferric-transferrin reductase
  • EC 1.16.1.3: aquacobalamin reductase
  • EC 1.16.1.4: cob(II)alamin reductase
  • EC 1.16.1.5: aquacobalamin reductase (NADPH)
  • EC 1.16.1.6: cyanocobalamin reductase (cyanide-eliminating)
  • EC 1.16.1.7: ferric-chelate reductase
  • EC 1.16.1.8: (methionine synthase) reductase

EC 1.16.3 With oxygen as acceptor

EC 1.16.8 With flavin as acceptor

  • EC 1.16.8.1: cob(II)yrinic acid a,c-diamide reductase

EC 1.17 Acting on CH or CH2 groups

EC 1.17.1 With NAD or NADP as acceptor

  • EC 1.17.1.1: CDP-4-dehydro-6-deoxyglucose reductase
  • EC 1.17.1.2: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase
  • EC 1.17.1.3: leucoanthocyanidin reductase
  • EC 1.17.1.4: xanthine dehydrogenase
  • EC 1.17.1.5: nicotinate dehydrogenase

EC 1.17.3 With oxygen as acceptor

  • EC 1.17.3.1: pteridine oxidase
  • EC 1.17.3.2: xanthine oxidase
  • EC 1.17.3.3: 6-hydroxynicotinate dehydrogenase

EC 1.17.4 With a disulfide as acceptor

EC 1.17.5 With a quinone or similar compound as acceptor

  • EC 1.17.5.1: phenylacetyl-CoA dehydrogenase

EC 1.17.99 With other acceptors

  • EC 1.17.99.1: 4-cresol dehydrogenase (hydroxylating)
  • EC 1.17.99.2: ethylbenzene hydroxylase
  • EC 1.17.99.3: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase

EC 1.18 Acting on iron-sulfur proteins as donors

EC 1.18.1 With NAD+ or NADP+ as acceptor

  • EC 1.18.1.1: rubredoxin—NAD+ reductase
  • EC 1.18.1.2: ferredoxin—NADP+ reductase
  • EC 1.18.1.3: ferredoxin—NAD+ reductase
  • EC 1.18.1.4: rubredoxin—NAD(P)+ reductase

EC 1.18.2 With dinitrogen as acceptor (transferred to EC 1.18.6)

  • EC 1.18.2.1: now EC 1.18.6.1

EC 1.18.3 With H+ as acceptor

  • EC 1.18.3.1: now EC 1.18.99.1

EC 1.18.6 With dinitrogen as acceptor

EC 1.18.96 With other, known, acceptors

  • EC 1.18.96.1: now EC 1.15.1.2

EC 1.18.99 With H+ as acceptor

  • EC 1.18.99.1: now EC 1.12.7.2

EC 1.19 Acting on reduced flavodoxin as donor

EC 1.19.6 With dinitrogen as acceptor

  • EC 1.19.6.1: nitrogenase (flavodoxin)

EC 1.20 Acting on phosphorus or arsenic in donors

EC 1.20.1 Acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor

  • EC 1.20.1.1: phosphonate dehydrogenase

EC 1.20.4 Acting on phosphorus or arsenic in donors, with disulfide as acceptor

  • EC 1.20.4.1: arsenate reductase (glutaredoxin)
  • EC 1.20.4.2: methylarsonate reductase

EC 1.20.98 Acting on phosphorus or arsenic in donors, with other, known acceptors

  • EC 1.20.98.1: arsenate reductase (azurin)

EC 1.20.99 Acting on phosphorus or arsenic in donors, with other acceptors

  • EC 1.20.99.1: arsenate reductase (donor)

EC 1.21 Acting on X-H and Y-H to form an X-Y bond

EC 1.21.3 With oxygen as acceptor

  • EC 1.21.3.1: isopenicillin-N synthase
  • EC 1.21.3.2: columbamine oxidase
  • EC 1.21.3.3: reticuline oxidase
  • EC 1.21.3.4: sulochrin oxidase ((+)-bisdechlorogeodin-forming)
  • EC 1.21.3.5: sulochrin oxidase ((-)-bisdechlorogeodin-forming)
  • EC 1.21.3.6: aureusidin synthase

EC 1.21.4 With a disulfide as acceptor

  • EC 1.21.4.1: D-proline reductase (dithiol)
  • EC 1.21.4.2: glycine reductase
  • EC 1.21.4.3: sarcosine reductase
  • EC 1.21.4.4: betaine reductase

EC 1.21.99 With other acceptors

  • EC 1.21.99.1: b-cyclopiazonate dehydrogenase

EC 1.97 Other oxidoreductases

EC 1.97.1

  • EC 1.97.1.1: chlorate reductase
  • EC 1.97.1.2: pyrogallol hydroxytransferase
  • EC 1.97.1.3: sulfur reductase
  • EC 1.97.1.4: (formate-C-acetyltransferase)-activating enzyme
  • EC 1.97.1.5: now *EC 1.20.4.1
  • EC 1.97.1.6: now *EC 1.20.99.1
  • EC 1.97.1.7: now *EC 1.20.4.2
  • EC 1.97.1.8: tetrachloroethene reductive dehalogenase
  • EC 1.97.1.9: selenate reductase
  • EC 1.97.1.10: thyroxine 5'-deiodinase
  • EC 1.97.1.11: thyroxine 5-deiodinase

EC 1.98 Enzymes using H2 as reductant

EC 1.98.1

  • EC 1.98.1.1: now EC 1.18.99.1

EC 1.99 Other enzymes using O2 as oxidant

EC 1.99.1 Hydroxylases (now covered by EC 1.14)

  • EC 1.99.1.1: deleted, now *EC 1.14.14.1
  • EC 1.99.1.2: deleted, now *EC 1.14.16.1
  • EC 1.99.1.3: deleted
  • EC 1.99.1.4: deleted
  • EC 1.99.1.5: deleted, now *EC 1.14.13.9
  • EC 1.99.1.6: deleted
  • EC 1.99.1.7: deleted, now *EC 1.14.15.4
  • EC 1.99.1.8: deleted
  • EC 1.99.1.9: deleted, now *EC 1.14.99.9
  • EC 1.99.1.10: deleted
  • EC 1.99.1.11: deleted, now *EC 1.14.99.10
  • EC 1.99.1.12: deleted
  • EC 1.99.1.13: deleted, covered by *EC 1.14.99.7 and *EC 5.4.99.7
  • EC 1.99.1.14: deleted, now *EC 1.13.11.27

EC 1.99.2 Oxygenases (now covered by EC 1.13)

  • EC 1.99.2.1: deleted, now *EC 1.13.11.12
  • EC 1.99.2.2: deleted, now *EC 1.13.11.1
  • EC 1.99.2.3: deleted, now *EC 1.13.11.3
  • EC 1.99.2.4: deleted, now *EC 1.13.11.4
  • EC 1.99.2.5: deleted, now *EC 1.13.11.5
  • EC 1.99.2.6: deleted, now *EC 1.13.99.1
v • d • e
Proteins: enzymes
TopicsActive site - Allosteric regulation - Binding site - Catalytically perfect enzyme - Coenzyme - Cofactor - Cooperativity - EC number
Enzyme catalysis - Enzyme inhibitor - Enzyme kinetics - Lineweaver-Burk plot - Michaelis-Menten kinetics - List of enzymes
TypesEC1 Oxidoreductases/list - EC2 Transferases/list - EC3 Hydrolases/list - EC4 Lyases/list - EC5 Isomerases/list - EC6 Ligases/list
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "List_of_EC_numbers_(EC_1)". A list of authors is available in Wikipedia.
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