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Oxazole is the parent compound for vast class of heterocyclic aromatic organic compounds. These are azoles with an oxygen and a nitrogen separated by one carbon .
Additional recommended knowledge
In biomolecules, oxazoles result from the cyclization and oxidation of serine or threonine nonribosomal peptides:
Oxazoles are not as abundant in biomolecules as the related thiazoles with oxygen replaced by a sulfur atom.
Oxazoles are aromatic compounds but less so than the thiazoles. Oxazole is a weak base with pKa of conjugate acid of 0.8 compared to 7 for imidazole.
Classical oxazole synthetic methods in organic chemistry are
Other methods are reported in the literature.
Categories: Oxazoles | Simple aromatic rings
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Oxazole". A list of authors is available in Wikipedia.|