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Transient receptor potential channel
Transient receptor potential or TRP channels are a family of loosely related ion channels that are non-selectively permeable to cations, including calcium and magnesium. TRP channels are so named because they were discovered in mutant drosophila that, instead of having sustained photoreceptor activity in response to light, have only a transient response to light. Most TRP channels are comprised of 6 membrane-spanning helices with intracellular N- and C-termini. TRP channels are activated and regulated by a wide variety of stimuli and are expressed widely throughout the body.
Additional recommended knowledge
They are encoded by at least 33 channel subunit genes divided into six sub-families:
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Transient_receptor_potential_channel". A list of authors is available in Wikipedia.|