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28 Current news about the topic enantiomers

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A novel strategy to generate useful chiral compounds

Newly designed ligands for a catalytic reaction to synthesize drugs and useful compounds

01-Jul-2020

Currently, various therapeutic compounds in the market, such as proteins, enzymes, and amino acids, are "chiral compounds"--molecules with two structures that are "mirror" images of each other but cannot be superimposed. Although the two variants of the molecule, also called "enantiomers," are ...

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Using corkscrew lasers to separate mirror molecules

Innovative approach could deepen insight into the mysterious handedness of life

13-Dec-2019

Many of the molecular building blocks of life have two versions that are mirror images of one another, known as enantiomers. Although seemingly identical, the two enantiomers can have completely different chemical behaviour – a fact that has major implications in our day-to-day lives. For ...

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Two chiral catalysts working hand in hand

Chemists develop a synthetic method providing access to different stereoisomers of a molecule

05-Dec-2019

Just as our left hand is not superposable to our right hand, the mirror image of certain molecules cannot be overlapped onto it, even when turned or twisted. These two mirror images are referred to by chemists as enantiomers and the molecule is said to be chiral. Chirality, which is a word ...

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Observing changes in the chirality of molecules in real time

19-Nov-2019

Chiral molecules - compounds that are mirror images of each other - play an important role in biological processes and in chemical synthesis. Chemists at ETH Zurich have now succeeded for the first time in using ultrafast laser pulses to observe changes in chirality during a chemical reaction in ...

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Scientists synthesized light with new intrinsic chirality to tell mirror molecules apart

Let there be… a new light

30-Oct-2019

Light is the fastest way to distinguish right- and left-handed chiral molecules, which has important applications in chemistry and biology. However, ordinary light only weakly senses molecular handedness. Researchers from the Max Born Institute for Nonlinear Optics and Short Pulse Spectroscopy ...

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Chirality in 'real-time'

Circular dichroism in the deep ultraviolet

11-Jan-2019

In nature, certain molecules with the same chemical composition, can exist in two different shapes that are mirrors images of each other, much like our hands. This property is known as "chirality" and molecules with different chirality are called enantiomers. Enantiomers can exhibit entirely ...

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Photochemical deracemization of chiral compounds achieved

The vanished mirror image

20-Dec-2018

Enantiomeric molecules resemble each other like right and left hands. Both variants normally arise in chemical reactions. But frequently only one of the two forms is effectual in biology and medicine. Hitherto, completely converting this mixture into the desired enantiomer was deemed impossible. ...

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Hybrid catalyst with high enantiomer selectivity

10-Aug-2018

A group of Japanese researchers has developed a technology to create a hybrid catalyst from simple-structured, commercially available rhodium and organic catalysts, which reduces chemical waste and produces molecules with high selectivity of an enantiomer, a pair of molecular structures that are ...

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Two new ways to fluorinated structures

Chemo-enzymatic synthesis of fluorinated antibiotics

07-Aug-2018

Fluorinated structures make up more than 20 percent of modern drugs, but benign and fast fluorination schemes are scarce. In a study scientists have now combined dynamic kinetic resolution and nucleophilic fluorination for the asymmetric synthesis of florfenicol, a veterinary antibiotic. After ...

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Polarized light: A simple route to highly chiral materials

11-May-2018

Chirality is at the heart of chemical research and much technology. For organic chemists, choosing between the left- and right-handed isomers of molecules is all part of a day's work. However, many solid materials also have enantiomeric forms, giving rise to a range of applications. Organic ...

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