Chemists discover simple way to build bigger molecules – one carbon at a time

This breakthrough method could accelerate drug discovery and the design of complex chemical products

12-Jun-2025 - A team of chemists at the University of Cambridge has developed a powerful new method for adding single carbon atoms to molecules more easily, offering a simple one-step approach that could accelerate drug discovery and the design of complex chemical products. The research, recently published in ...

New process for polarity inversion of chemical compounds for precise drug synthesis

“With this research, we believe we have made a significant contribution to selective, sustainable and targeted chemical synthesis”

22-Jan-2025 - Researchers at Leipzig University have developed a new process for reversing the polarity of chemical compounds, also known as umpolung, for the precise synthesis of pharmaceuticals. This innovative method, developed by a team of scientists led by Professor Christoph Schneider at the Institute of ...

Breaking bonds to form bonds: Rethinking the Chemistry of Cations

New chemical reaction with potential applications in medicinal chemistry

22-May-2024 - A team of chemists from the University of Vienna, led by Nuno Maulide, has achieved a significant breakthrough in the field of chemical synthesis, developing a novel method for manipulating carbon-hydrogen bonds. This groundbreaking discovery provides new insights into the molecular interactions ...

Intrepid early-career researchers who are fearlessly tackling difficult global problems

Talented 12: Chemical & Engineering News announces its 2023 rising stars in chemistry

23-May-2023 - Chemical & Engineering News (C&EN), an independent news outlet of the American Chemical Society (ACS), has unveiled its annual “Talented 12” list. The list highlights early-career researchers in the chemical sciences who are fearlessly tackling difficult global problems. These intrepid innovators ...

A better route to benzocyclobutenes, sought-after buildingblocks for drugs

Scripps Research chemists devise a new, C-H activation-based method for the synthesis of BCBs

16-May-2023 - Scripps Research chemists have solved a long-standing problem in the field of pharmaceutical chemistry with a relatively simple and controllable method for making benzocyclobutenes (BCBs)—a class of reactive compounds that are highly valued as building blocks for drug molecules, but have been ...

Breakthrough in the production of three-dimensional molecular structures

New dimensions in organic chemistry through light-mediated synthesis

07-Apr-2021 - A major goal of organic and medicinal chemistry in recent decades has been the rapid synthesis of three-dimensional molecules for the development of new drugs. These drug candidates exhibit a variety of improved properties compared to predominantly flat molecular structures, which are reflected ...

Researchers at the forefront of developing machine learning methods for chemical discovery

Machine learning to help identify drug candidates

23-Oct-2020 - Prof. Alexandre Tkatchenko and his research team at the University of Luxembourg have been awarded grants totalling 500,000 euros to conduct research in the emerging field of machine learning methods for chemical discoveries. The discovery and formulation of new drugs, antivirals, antibiotics and ...

ChemMaps lets researchers navigate the chemical universe

06-Jun-2018 - Researchers from North Carolina State University have created a new online service - ChemMaps - that allows users to interactively navigate the chemical space of over 8,000 drugs and 47,000 environmental compounds in 3D and real time. ChemMaps is designed to be a central resource for students and ...

New chemical synthesis method can produce an exciting range of novel compounds

06-Jul-2017 - Chemists at Nagoya Institute of Technology have developed an innovative chemical reaction system, which could have applications for developing starter molecules for additional synthetic procedures in organic chemistry, as well as pharmaceutical candidates with a potentially wide range of ...

State-of-the-art text mining technologies for chemistry

23-Jun-2017 - The Biological Text Mining Unit at the Spanish National Cancer Research Centre (CNIO) together with with researchers at the Center for Applied Medical Research (CIMA), of the University of Navarra, in Pamplona, and the Barcelona Supercomputing Centre (BSC-CNS) have published the first exhaustive ...