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Formulation systems: KNAUER IJM NanoScaler

System for lipid nanoparticle formulation research

KNAUER Wissenschaftliche Geräte GmbH

Determine conditions for optimal API encapsulation results

Scalable results: can be transfered to large-scale KNAUER IJM equipment

Produce amounts enough for in vitro studies and small-scale production

Benchtop LNP formulation system for research and development as well as small-scale production

The IJM NanoScaler system is designed for lipid nanoparticle R&D – allowing scientists to determine the optimal process parameters for the formulation of API-containing lipid nanoparticles. These active pharmaceutical ingredients include complex or delicate API like RNA, mRNA, siRNA, and DNA-based molecules, or products that need specific entry into target cells.

Equipped with KNAUER’s lipid nanoparticle producing Impingement Jets Mixing (IJM) technology the NanoScaler allows researchers to optimize encapsulation conditions for their nucleotide-based therapy before scaling up the process to run on a larger GMP-compliant IJM NanoProducer unit. The benchtop system comes with five different KNAUER IJM units to help researchers determine optimum encapsulation conditions – custom mixing units can also be used.

The IJM NanoScaler can produce lipid-encapsulated API at a range from 1 mL to hundreds of milliliters meaning the system is perfect for proof-of-concept testing and process optimization, pre-clinical trials e.g. for in vitro studies, as well as small-scale production.

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System for lipid nanoparticle formulation research and small-scale production

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KNAUER IJM NanoScaler - Functional units

Product classification

Applications

lipid nanoparticles
LNP
mRNA
novel therapies
nucleotids
pre-clinical

Product categories

API
API-loaded lipid nanoparticles
formulation systems
Lipid Nanoparticles
production systems

Target Industries

Biotechnology
Pharma

Request product information now

Formulation systems: KNAUER IJM NanoScaler

System for lipid nanoparticle formulation research

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