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5 Current white paper about the topic spectrometers

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Structural and Chemical 3D Imaging with AFM and Raman.

12-10-2010

In the Life Sciences and Bio-medical Research, the characterization of chemical compounds within cells or tissues is one of the most important and difficult tasks for researchers to perform. The development of pharmaceuticals such as drug delivery coatings or capsules also requires as much information as possible about their chemical and structural compositions. For the fields of nanotechnology and materials science, a thorough knowledge of the samples' surface morphology on a sub-micron scale is essential...

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Chemometric Spectroscopy

Modular Software for Routine Analysis

26-02-2007

Chemometric Spectroscopy is the term used to describe the direct combination of a spectroscopic measurement with a chemometric data evaluation procedure, typically a multivariate statistic method, so providing quick and reliable deduction of the qualitative and quantitative properties of a sample from its spectrum. A multi-linear regression (MLR) or partial least squares (PLS) regression is usually used for the quantitative determination of individual or combined parameters, while substance identification generally relies on techniques such as discriminant or cluster analysis....

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UV/Vis/NIR Spectrometry for the Film Thickness Determination of Transparent Films and Layers

08-09-2005

Within nearly all branches of industry we find products, which are coated with thin transparent layers to improve the surface features: Window sheet glasses obtain changes in reflection and absorption behavior, ceramics are treated with coatings to lower water adhesion, coatings on metals create corrosion resistance or better sliding factors. Transparent coatings play also a major role in the semiconductor business. One of the important features to be determined and controlled is the thickness of the layers to balance performance and material input during development and production...

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The Determination of Hazardous Substances According to RoHS and WEEE Directives

28-08-2005

1st July 2006 is an important deadline for the electro- and electronics industries. This date bans hazardous substances like lead, cadmium, mercury, hexavalent chromium and polybrominated biphenyls and diphenyl ethers from electro- and electronic equipment. This restriction, even though in discussion since 1991, has become more and more important from year to year because of tons of electronic waste releasing toxic substances which are accumulated in the environment, the food chain and all human beings. In order to enforce the substances ban and the limitation or substitution of hazardous components, elemental analysis is obviously the most important control measure for monitoring limiting values. This requires precise analytical systems such as X-ray fluorescence, ICP- and atomic absorption spectrometers. These instruments are able to detect trace concentrations of hazardous compounds - for example cadmium, using an atomic absorption spectrometer in the flame atomization mode up to 0.1 mg/L, or using the di...

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Accurate Mass and TIPTM: Two Dimensions for Elemental Composition Determination: microTOFTM Featuring Unique TIPTM

10-03-2005

The ESI-TOF mass spectrometers micrOTOF and micrOTOF focus do not only provide accurate mass measurements but additionally describe the True Isotopic Pattern TIPTM. For molecular formula generation this unique combination significantly reduces the number of possible formula candidates and the elemental composition of compounds with molecular weights far higher than 500 Da can unequivocally be determined...

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