Surface enhanced Raman sensing (SERS) has expanded the applications of Raman spectroscopy to include trace analysis of materials such as explosives residues, evidence at crime scenes, chemical warfare agents and pesticides. As a label-free technique, SERS is also well suited to biosensing, from blood glucose to diagnosis of diseases like cancer, Alzheimer’s and Parkinson’s. A new variant of SERS developed by a group at Jackson State University in Mississippi, U.S., uses a hybrid probe composed of graphene oxide attached to a popcorn-shaped gold nanoparticle to achieve ultrasensitive sensing of HIV and MRSA DNA characteristics.
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