Chemical Synthesis

Companies Chemical Synthesis

ChiroBlock GmbH, Germany

Contract research on chemical syntheses and research chemicals. Since 1999 we have been a reliable partner of research departments serving the life-scinece industries and companies engaged in cosmetics, new materials, sensors - with a demand for new molecules and exclusively developed synthesis rout more

Chemspeed Technologies AG, Switzerland

Chemspeed is a global leader in the development of innovative instruments and consumables for scientists working in research and development laboratories including a line of fully automated parallel synthesizers, instruments for high throughput solid dispensing and liquid handling, and workstations more

CEM GmbH, Germany

CEM is the leading provider of microwave solutions for the laboratory, industrial and scientific marketplace. Since creating this market 20 years ago, we have sold almost 20,000 systems. Despite this obvious success, we believe microwave chemistry is still an emerging technology and presents tremend more

News Chemical Synthesis

• Novel computer-assisted chemical synthesis method cuts research time and cost
  

  Hokkaido University scientists have succeeded in synthesizing an α,α-difluoroglycine derivative, a type of α-amino acid, based on a reaction path predicted by quantum chemical calculations. This novel method, combining experimental chemistry and computational chemistry, could innovate the developmen more

• A chemical factory for all cases
  

  In the future, bottlenecks in the supply of medicines could be more easily eliminated. An automated machine for radial synthesis developed by chemists at the Max Planck Institute of Colloids and Interfaces will enable the flexible production of medical agents and other chemical products. The apparat more

• A cheaper way to scale up atomic layer deposition
  

  Atomic layer deposition (ALD) involves stacking layers of atoms on top of each other like pancakes. The atoms come from a vaporized material called a precursor. ALD is a well-established technique for manufacturing microelectronics like semiconductors and magnetic heads for sound recording, as well more

White papers Chemical Synthesis

• Innovative Techniques to Synthesize Breakthrough Molecules
  

  Four case studies highlight how top pharmaceutical companies are implementing new synthesis techniques and the impact on the chemical synthesis lab more

• Chemical Synthesis – a new and versatile way to multifunctional [cd,lm]-annellated Perylenes and their Homlogues
  

  The method presented here for producing multifunctional Pyrenes, Perylenes and other homologue compounds provides a very flexible and effective route more

Publications Chemical Synthesis

• The discovery of a freezing-induced peptide ligation during the total chemical synthesis of human interferon-ε

  A counterintuitive freezing-induced peptide ligation was discovered in the total synthesis of human interferon-ε (hIFN-ε) which blocks HIV infection through unique mechanisms. The successful synthesis of hIFN-ε (187 amino acids) in this research laid the foundation for related anti-AIDS drug develop more

• Synthesis of Hydrophobic Insulin-based Peptides Using a Helping-Hand Strategy

  The introduction of solid-phase peptide synthesis in the 1960’s improved the chemical synthesis of both the A- and B-chains of insulin and insulin analogs. However, the subsequent elaboration of the synthetic peptides to generate active hormones continues to be difficult and complex due in part to t more

• Plant extracts as green reductants for the synthesis of silver nanoparticles: Lessons from chemical synthesis

  The increasing use of silver (Ag) nanoparticles (NPs) in daily-life applications, elec-tronics, or catalysis calls for green and cost-efficient synthetic methods. Ag NPs are used especially in biomedicine because of their antibacterial, antifungal or anticancer properties. The chemical synthesis all more