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Clofibrate



Clofibrate
Systematic (IUPAC) name
ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
Identifiers
CAS number 637-07-0
ATC code C10AB01
PubChem 2796
DrugBank APRD00879
Chemical data
Formula C12H15ClO3 
Mol. mass 242.698 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding Variable, 92–97% at therapeutic concentrations
Metabolism Hydrolyzed to clofibric acid; hepatic glucuronidation
Half life Highly variable; average 18–22 hours. Prolonged in renal failure
Excretion Renal, 95 to 99%
Therapeutic considerations
Pregnancy cat.

B1(AU) C(US)

Legal status

-only(US)

Routes Oral

Clofibrate is a fibrate. It is used in the treatment of cardiovascular disease.

Additional recommended knowledge


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Clofibrate". A list of authors is available in Wikipedia.
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