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Mevastatin



Mevastatin
Systematic (IUPAC) name
Compactin
Identifiers
CAS number 73573-88-3
ATC code  ?
PubChem 64715
DrugBank EXPT00012
Chemical data
Formula C23H36O6 
Mol. mass 408.534 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Mevastatin, compactin, ML-236B is a hypolipidemic agent that belongs to the statins class.

Additional recommended knowledge

It was the first compound isolated in the 70s during research into HMG-CoA reductase inhibitors produced by a mould Penicillium citrinum.

Mevastatin is not used in therapy of hyperlipidemias because of multiple side effects but it is the only source for production of other statin - pravastatin.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Mevastatin". A list of authors is available in Wikipedia.
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