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Danaparoid



Danaparoid
Systematic (IUPAC) name
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ATC code B01AB09
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Danaparoid sodium (Orgaran®) is an anticoagulant that works by inhibiting activated factor X (factor Xa).

Danaparoid is considered a "low molecular weight heparin" by some sources, but is chemically distinct from heparin and thus has little cross-reactivity in heparin-intolerant patients.

Additional recommended knowledge

Contents

Uses

It is used to prevent deep venous clots, particularly in situations with a high risk of clot formation, such as after hip surgery.

It is also used as a heparinoid substitute in heparin-induced thrombocytopenia which may otherwise cause paradoxical thrombosis.

Discontinuation

On August 14, 2002, this drug was withdrawn by Organon International.[1]

Administration

IV IV and SC

Side effects

  • Bleeding problems
  • Low platelets, due to a low level of structural similarity between danaparoid and heparin
  • Asthma exacerbations, due to allergies to sulphites contained within the medicine

References

  1. ^ Danaparoid (Subcutaneous Route) - MayoClinic.com. Retrieved on 2007-08-23.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Danaparoid". A list of authors is available in Wikipedia.
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