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Systematic (IUPAC) name
5-butanoic acid
CAS number 88430-50-6
88475-69-8 (sodium salt)
ATC code B01AC19
PubChem 5282428
Chemical data
Formula C24H30O5 
Mol. mass 398.492 g/mol
Pharmacokinetic data
Bioavailability 50–70%
Metabolism Unknown
Half life 35–40 minutes
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status


Routes Oral

Beraprost is a synthetic analogue of prostacyclin, under clinical trials for the treatment of pulmonary hypertension. It is also being studied for use in avoiding reperfusion injury.

Clinical pharmacology

As an analogue of prostacyclin PGI2, beraprost effects vasodilation, which in turn lowers the blood pressure. Beraprost also inhibits platelet aggregation, though the role this phenomenon may play in relation to pulmonary hypertension has yet to be determined.

Dosage and administration

Beraprost is administered orally as a pill.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Beraprost". A list of authors is available in Wikipedia.
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