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Travoprost



Travoprost
Systematic (IUPAC) name
propan-2-yl 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)
phenoxy]-but-1-enyl]-cyclopentyl]hept-5-enoate
Identifiers
CAS number 157283-68-6
ATC code S01EE04
PubChem 656627
DrugBank APRD01271
Chemical data
Formula C26H35F3O6 
Mol. mass 500.548 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C US

Legal status

Schedule VI US

Routes Topical (eye drops)

Travoprost ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes.[1] It is also known by the brand name of Travatan, manufactured by Alcon Inc. Travoprost is a synthetic prostaglandin F 2α analogue. Its chemical name is isopropyl (Z)-7- [(1 R ,2 R ,3 R ,5 S )-3,5-dihydroxy-2-[(1 E ,3 R )-3-hydroxy-4-[(α,α,α-trifluoro- m -tolyl)oxy]-1- butenyl]cyclopentyl]-5-heptenoate.[2]

Additional recommended knowledge

Possible side effects of this medication are:

  • May cause blurred vision;
  • May cause eyelid redness;
  • May permanently darken eyelashes;
  • May cause eye discomfort;
  • May eventually cause permanent darkening of the iris to brown (heterochromia);
  • May cause a temporary burning sensation during use.
  • May cause thickening of the eyelashes.

References

  • http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/500293.html


Notes

  1. ^ [1]
  2. ^ [2]
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Travoprost". A list of authors is available in Wikipedia.
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