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Latanoprost



Latanoprost
Systematic (IUPAC) name
propan-2-yl 7-[3,5-dihydroxy-2- (3-hydroxy-5-phenyl-pentyl) -cyclopentyl] hept-5-enoate
Identifiers
CAS number 130209-82-4
ATC code S01EE01
PubChem 60798
DrugBank APRD01065
Chemical data
Formula C26H40O5 
Mol. mass 432.593 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 17 minutes
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes Topical (eye drops)

Latanoprost (pronounced la-TA-noe-prost) ophthalmic solution is a topical medication used for controlling the progression of glaucoma or ocular hypertension, by reducing intraocular pressure. It is a prostaglandin analogue that works by increasing the outflow of aqueous fluid from the eyes.

Additional recommended knowledge

It is also known by the brand name of Xalatan manufactured by Pfizer.

Side effects

Possible side effects:

  • May cause reddening of the eyes (hyperemia)
  • May cause blurred vision;
  • May cause eyelid redness;
  • May permanently darken eyelashes;
  • May cause eye discomfort;
  • May eventually cause permanent darkening of the iris to brown (heterochromia);
  • May cause a temporary burning sensation during use.
  • May cause thickening of the eyelashes.
  • Rarely, herpes simplex keratitis.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Latanoprost". A list of authors is available in Wikipedia.
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