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Brinzolamide



Brinzolamide
Systematic (IUPAC) name
(5R)-5-ethylamino-3-(3-methoxypropyl)-
2,2-dioxo-2λ6,9-dithia-
3-azabicyclo[4.3.0]nona-7,10-diene-
8-sulfonamide
Identifiers
CAS number 138890-62-7
ATC code S01EC04
PubChem 68844
DrugBank APRD00475
Chemical data
Formula C12H21N3O5S3 
Mol. mass 383.51 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding ~60%
Metabolism  ?
Half life 111 days
Excretion  ?
Therapeutic considerations
Licence data

EU US

Pregnancy cat.

C(US)

Legal status

-only(US)

Routes Ophthalmic

Brinzolamide is a carbonic anhydrase inhibitor.

Additional recommended knowledge

References

  • Ermis S, Ozturk F, Inan U (2005). "Comparing the effects of travoprost and brinzolamide on intraocular pressure after phacoemulsification.". Eye 19 (3): 303-7. PMID 15258611.
  • Iester M, Altieri M, Michelson G, Vittone P, Traverso C, Calabria G. "Retinal peripapillary blood flow before and after topical brinzolamide.". Ophthalmologica 218 (6): 390-6. PMID 15564757.
  • Kaup M, Plange N, Niegel M, Remky A, Arend O (2004). "Effects of brinzolamide on ocular haemodynamics in healthy volunteers.". Br J Ophthalmol 88 (2): 257-62. PMID 14736787.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Brinzolamide". A list of authors is available in Wikipedia.
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