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Systematic (IUPAC) name
N-(3-methyl-5-sulfamoyl-3H- 1,3,4-thiadiazol-2-ylidene) ethanamide
CAS number 554-57-4
ATC code S01EC05
PubChem 4100
DrugBank APRD00740
Chemical data
Formula C5H8N4O3S2 
Mol. mass 236.274 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 55%
Metabolism  ?
Half life 14 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status


Routes Oral

Methazolamide (Neptazane®) is a carbonic anhydrase inhibitor.


  • Iyer G, Bellantone R, Taft D (1999). "In vitro characterization of the erythrocyte distribution of methazolamide: a model of erythrocyte transport and binding kinetics.". J Pharmacokinet Biopharm 27 (1): 45-66. PMID 10533697.
  • RxList. Neptazane. Retrieved on August 20, 2006.
  • Shirato S, Kagaya F, Suzuki Y, Joukou S (1997). "Stevens-Johnson syndrome induced by methazolamide treatment.". Arch Ophthalmol 115 (4): 550-3. PMID 9109770.
  • Skorobohach B, Ward D, Hendrix D (2003). "Effects of oral administration of methazolamide on intraocular pressure and aqueous humor flow rate in clinically normal dogs.". Am J Vet Res 64 (2): 183-7. PMID 12602587.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Methazolamide". A list of authors is available in Wikipedia.
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