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Glycoprotein IIb/IIIa inhibitors
In medicine, glycoprotein IIb/IIIa inhibitors, also GpIIb/IIIa inhibitors, is a class of antiplatelet agents.
Additional recommended knowledge
Several GpIIb/IIIa inhibitors exist:
Glycoprotein IIb/IIIa inhibitors are frequently used during percutaneous coronary interventions (angioplasty with or without intracoronary stent placement).
They may also be used to treat acute coronary syndromes, without percutaneous coronary intervention, depending on TIMI risk.
They should be given intravenously. The oral form is associated with increased mortality and hence should not be given.
Their development arose from the understanding of Glanzmann's thrombasthenia, a condition in which the GpIIb/IIIa is lacking.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Glycoprotein_IIb/IIIa_inhibitors". A list of authors is available in Wikipedia.|