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Padimate O

Padimate O
IUPAC name 4-dimethylaminobenzoic acid 2-ethylhexyl ester
Other names 2-ethylhexl dimethyl PABA
Escalol 507
CAS number 21245-02-3
PubChem 30541
Molecular formula C17H27NO2
Molar mass 277.402
Density 0.99 g/cm³
Melting point

<25 °C

Boiling point

362 °C

Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Padimate O is an organic compound that is an ingredient in some sunscreens. It is a derivative of PABA, an ester formed by the condensation of 2-ethylhexanol and dimethylaminobenzoic acid. It is a yellowish oily liquid that is insoluble in water. It absorbs ultraviolet rays, thereby preventing direct DNA-damage by UV-B. Unfortunately the excited padimate O molecule reacts bimolecularly with DNA and produces indirect DNA-damages, that are similar to those done by ionizing radiation. Therfore padimate o is presumably photocarcinogenic.[1]

Additional recommended knowledge

See also


  1. ^ Melanie Gulston, John Knowland; S. H. Moss, D. J. Davies (1999). "Illumination of human keratinocytes in the presence of sunscreen ingredient padimat-O .... increases strand breaks.". Mutation Research 1999 (444): 49-60.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Padimate_O". A list of authors is available in Wikipedia.
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