31-Aug-2009 - Uniqsis Ltd

Flow Chemistry Scale Up for Microwave Reactions

Three new Application Notes from Uniqsis Ltd, manufacturers of the FlowSyn™ Continuous Flow Reactor, describe how the system can reproduce and scale up reactions that have been developed using small scale batch reactions in a microwave reactor.

Microwave reactors are frequently used for small scale batch chemistry. However due to the extremes of temperature and pressure reached in a microwave it is often difficult to transfer these reactions to conventional non-microwave apparatus for subsequent development, leading to difficulties with scaling studies. The standard FlowSyn system can mimic the conditions created in a microwave reactor, and since in flow chemistry the quantity of material produced is limited only by the reaction time, scaling can be achieved.

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