Varian, Inc. (Nasdaq: VARI) - June 06, 2001
- today introduced the PrepStar™ 218 benchtop preparative high
performance liquid chromatography (HPLC) system. With a higher
flow/pressure pump and enhanced control software, the system
sets a new price and performance standard for pharmaceutical and
bio-science labs purifying drug active ingredients for testing and
trials prior to the manufacturing step.
"The PrepStar™ 218 gives Varian the most complete portfolio
of preparative chromatography systems available, from a single
supplier, providing customers with systems to suit any process
need or budget," said Allen J. Lauer, president and CEO of Varian,
Inc. "With the PrepStar 218, labs with basic purification needs
now have access to superior entry-level system performance,
backed by Varian's worldwide support and expertise in preparative
chromatography, all at a lower price than competitive systems."
Varian, Inc's. preparative chromatography offerings include
flash chromatography for the rapid purification of small amounts
of compounds; analytical/preparative HPLC systems used
throughout the drug discovery and development process;
preparative systems for recovering compounds for testing/trials;
and process systems used to recover compounds in large volumes
for pharmaceutical production. All Varian systems are based on
the same control software platform, making scale-up from the
laboratory bench to production a seamless and predictable
process, and helping speed new pharmaceuticals to market.
Unmatched in class and performance, the PrepStar 218
system combines capabilities of the 218 pump, LC ReSponderª
control software and the new PrepStar™ 530 fluidics module. The
new 218 pump features dramatically improved scale-up capability
with flow and pressure performance that permits flow rates of up
to 200 mL/minute at 4000 psi enabling greater flexibility in
column/sorbent selection for truly high performance purifications.
The 218 pump can be controlled with the Star® Workstation
software for analytical and basic preparative HPLC applications, or
with the new LC ReSponder process control software which
enables the use of the PrepStar 530 fluidics module, for greater
integrated fluid management control, such as sample injection,
gradient formation and fractionation/collection. These features
enable the user to deal with the purification operation in a more
Additionally, LC Responder software is designed to meet the
rigors of FDA validation with operator security as well as the
security of process records as standard features. System-specific
validation protocols are available. The enhanced software option
provides the user with a seamless and easy scale-up, from the
bench straight through to the production level, with the same
software platform being used on increasingly larger systems as
the process scales-up.
The new PrepStar 530 fluidics module gives users increased
control of the process stream from solvent selection through
fraction collection. The system can be customized to
accommodate various application requirements.
The complete PrepStar™ 218 system and the 218 pump alone
will be available for shipment in early July 2001.