New AI Method Revolutionises the Design of Enzymes

New Riff-Diff technology designs enzymes for chemical reactions efficiently and precisely in a one-shot process

23-Jan-2026 - Researchers at TU Graz and the University of Graz can use the technology to construct artificial biocatalysts. These new enzymes are significantly faster, more stable and more versatile than previous artificial biocatalysts. Enzymes with specific functions are becoming increasingly important in ...

Sustainable chemistry with the help of Artificial Intelligence

The new process could make an important contribution to more environmentally friendly production

03-Nov-2025 - Amidation reactions are the most common reactions in the chemical industry. They are indispensable for a wide range of industrial production processes, but their ecological footprint is highly problematic. They generate large amounts of toxic waste and are energy-intensive. A team led by Dr ...

Mechanochemistry strikes again: A facile means for generating organolithium molecules

Mechanochemistry using a ball mill demonstrates versatility for generating academically and industrially significant organolithium compounds

27-Feb-2025 - Organolithium compounds, molecules containing a carbon–lithium bond, are excellent precursors for building new carbon–carbon and other carbon–heteroatom bonds. They are widely utilized in both academia and industry for their applications in polymer synthesis, pharmaceuticals, and general organic ...

Extremely Low Friction Thanks to New Solid State Lubricant

By combining organic and inorganic chemistry, scientists developed the innovative lubricant - with remarkable capabilities

19-Feb-2025 - Finding the right lubricant for the right purpose is a task that is often extremely important in industry. Not only to reduce friction, overheating and wear, but also to save energy. At TU Wien, the research groups of Prof Carsten Gachot (Tribology, Mechanical Engineering) and Prof Dominik Eder ...

New process for polarity inversion of chemical compounds for precise drug synthesis

“With this research, we believe we have made a significant contribution to selective, sustainable and targeted chemical synthesis”

22-Jan-2025 - Researchers at Leipzig University have developed a new process for reversing the polarity of chemical compounds, also known as umpolung, for the precise synthesis of pharmaceuticals. This innovative method, developed by a team of scientists led by Professor Christoph Schneider at the Institute of ...

Carbon Atom Transfer

Spectacular basic research in organic chemistry

23-Jul-2024 - Professor Max Martin Hansmann from the Department of Chemistry and Chemical Biology and his team have developed a new reagent for selectively adding carbon atoms to molecules. This development is so spectacular for basic research in organic chemistry that it has been published in the prestigious ...

On the way to sustainable chemistry? Iron makes it possible

Hydroformylation of olefins using iron catalysis and light

22-Jul-2024 - The hydroformylation of olefins, also known as oxosynthesis, is one of the most important industrial processes in chemistry. Developed in 1938 by Otto Roehlen (Ruhrchemie), more than 10 million tons per year of so-called oxo products are now produced using this process. The main catalysts used ...

Machine learning and AI aiding in the prediction of chemical reaction outcomes

15-May-2024 - There are few problems now that AI and machine learning cannot help overcome. Researchers from the Yokohama National University use this modern advantage to overcome what conventional methods cannot. There are many rules to remember when it comes to the interaction of carbon-containing (or ...

Synthetic chemistry approach yields new compounds with potential biomedical applications

The study marks a significant advancement in chemical synthesis techniques, leveraging modern organic chemistry and engineered enzymes

10-May-2024 - Researchers at Rice University have successfully synthesized a group of natural compounds known as fusicoccanes. The molecules, found in various living organisms, exhibit diverse biological activities, including the ability to modulate protein-protein interactions within biological systems. The ...

Developing new types of batteries sustainably

16-Jan-2024 - "Conventional lithium-ion batteries are very powerful, but also expensive, as they require metals such as nickel and cobalt in addition to lithium," says chemist Prof Dr Yan Lu. "That's why I'm researching more sustainable alternatives, such as lithium-sulphur batteries and batteries based on ...