Synthesis

Companies Synthesis

MLS GmbH, Germany

more

Chemspeed Technologies AG, Switzerland

Chemspeed is a global leader in the development of innovative instruments and consumables for scientists working in research and development laboratories including a line of fully automated parallel synthesizers, instruments for high throughput solid dispensing and liquid handling, and workstations more

CEM GmbH, Germany

CEM is the leading provider of microwave solutions for the laboratory, industrial and scientific marketplace. Since creating this market 20 years ago, we have sold almost 20,000 systems. Despite this obvious success, we believe microwave chemistry is still an emerging technology and presents tremend more

Products Synthesis

High Throughput Flow Reactor for Process Chemists

The FlowSyn Maxi™ from Uniqsis is a high throughput flow reactor for process chemists looking to optimise reaction conditions before scaling-up synthetic production to multiple kilograms per day more

Real time monitoring and control of liquid processes

Real-time measurement in less than a second, independent of turbidity, colour, absorption, viscosity ✓ Process temperatures up to 150°C and ATEX certification ✓ Nearly unlimited mounting flexibility due to compact design and various adaptors more

Buchi nutsche filters for various applications in scale-up, pilot and production

Easy and safe operation ✓ Customized according to your process requirements ✓ cGmP and ATEX compliant ✓ more

Services Synthesis

Narrow PSD Spherical Particles in Micron Range by Drying / Core-Shell Coating / Calcination in One Step

Long-term stability for battery materials through precise, even coating of anode/cathode materials Unique new optical effects and maximum protection for your paint and coating pigments more

News Synthesis

• Ultraheavy precision polymers
  

  An environmentally friendly and sustainable synthesis of "heavyweight" polymers with very narrow molecular weight distributions is an important concept in modern polymer chemistry. Thanks to a new photoenzymatic process, Chinese researchers have been able to increase the range of possible monomers. more

• Chemists develop framework to enable efficient synthesis of 'information-dense' molecules

  A team led by scientists at Scripps Research has developed a theoretical approach that could ease the process of making highly complex, compact molecules. Such molecules are often found in plants and other organisms, and many are considered desirable starting points for developing potential new drug more

• Cascade from methanol to hydrogen
  

  Chemists at the Leibniz Institute for Catalysis (LIKAT) in Rostock are able to produce hydrogen from methanol under mild conditions of less than one hundred degrees Celsius and ambient pressure, with the yield and purity required for fuel cells. To achieve this, they optimized a proprietary process more

Videos Synthesis

Narrow PSD Spherical Particles in Micron Range by Drying / Core-Shell Coating / Calcination in One Step

From nano to micro: drying, coating and calcining in just one process step with synthesis reactors from Glatt. Produce and coat powder materials with new, previously unattained properties in the pulsating hot gas stream of the patented Glatt powder synthesis. Thanks to the particularly homogeneous t more

Berghof reactor technology - high- and low-pressure reactors, pressure vessels and metal-free reactors

NR low-pressure reactors, DB metal-free reactors and DAB pressure vessels.Smart instrument concepts allow an easy handling of all Berghof reactors. Due to helpful tools, opening and closure of the reactors is fast and with few effort. Extensive accessories support an efficient use of the reactors.Ru more

Improve Your Strategy for the Design of New Molecules

Science of Synthesis is your one-stop tool for full-text reviews of organic transformations and experimental procedures. The online reference work helps speed up your literature research and improve your strategy for the design of new molecules. Science of Synthesis provides a critical review of the more

White papers Synthesis

• Pfizer Evaluates New Automated Sampling Technique
  

  This paper reviews the advantages of automated sampling, and four case studies testing the practice of EasySampler at Pfizer for impurity profiling more

• Chemists Need Tools that Allow them to Better Profile Organo-Metallic Reactions
  

  Advantages of automated sampling in a case study testing the practice of EasySampler for reaction profiling of an organo-metallic reaction more

• Develop Syntheses More Efficiently: How to Save Time and Money by Laboratory Automation
  

  How to maximize the efficiency and quality of developing your synthesis through parallel method development using fully automated laboratory reactors more

Publications Synthesis

• Silver(I)-catalyzed sequential hydroamination and Prins type cyclization for the synthesis of fused benzo--sultams

  An intramolecular annulation strategy has been developed for the synthesis of tetrahydrobenzo[e]pyrano[4,3-c][1,2]thiazine derivatives by means of coupling of aldehydes with 2-(4-hydroxybut-1-yn-1-yl)-N-arylsulfonamides using a catalytic amount of silver hexafluoroantimonate in toluene at 80 °C. Thi more

• An efficient iodine pentoxide-triggered iodocarbocyclizations for the synthesis of iodooxindoles in water

  An efficient iodocarbocyclization of alkenes for the synthesis of iodooxindoles has been developed. This reaction proceeds in a chemoselective manner and shows excellent tolerance of various functional groups, including a chemosensitive hydroxymethyl group. Nonmetal inorganic iodine pentoxide was us more

• Copper-Catalyzed Cyclization of 2-Cyanobenzaldehydes and 2-Isocyanoacetates: an Efficient Strategy for the Synthesis of Substituted 1-Aminoisoquinolines

  A Cu(acac)2-catalyzed cyclization reaction of 2-cyanobenzaldehydes with 2-isocyanoacetates has been successfully developed providing an efficient strategy for the synthesis of substituted 1-aminoisoquinoline. The reaction proceeds smoothly under mild conditions with high efficiency, and might provid more

q&more articles Synthesis

• The Beginning of the End?
  

  Those of us who have been either directly involved in, or on the periphery of, the pharmaceutical industry over the last decade have seen at first hand a dramatic change. Times change, and technology changes. Take computer data storage for example. Not so long ago, the floppy disk was state of the art, replaced by the CD-ROM, and then by the USB drive. more

• Customized ligands pave the way for new reaction pathways
  

  For the first time, an efficient catalyst for palladium-catalyzed C–C bonding between aryl chlorides and alkyl lithium compounds has been found. This reaction enables simpler synthesis routes for important products, such as pharmaceuticals, while avoiding much salt waste. more

• With Light in the Fight against Malaria
  

  Malaria represents a global threat to health, which is difficult to keep under control. Amongst more than 200 million sufferers, over 500,000 die each year of the disease, with the risk of a fatal outcome being particularly high in children [1]. more

Authors Synthesis

• Mathies V. Evers
  

  Mathies Evers, born in 1989, studied chemistry at the Ruhr University Bochum, where he researched the synthesis of atom-precise molecular clusters. After his master's degree he started his doctoral thesis at the Chair of Analytical Chemistry II of Professor Dr. Kristina Tschulik and is supported by more

• Prof. Dr. Burkhard König
  

  Burkhard König, born in 1963, received his Ph.D. in 1991 from the University of Hamburg. He continued his scientific education as a post-doctoral fellow with Prof. M. A. Bennett, Research School of Chemistry, Australian National University, Canberra, and Prof. B. M. Trost, Stanford University. Since more

• Prof. Dr. Peter Seeberger
  

  born 1966, studied chemistry at the University of Erlangen-Nuremberg, and received his doctorate in biochemistry from the University of Colorado. After holding a post-doctorate position at the Sloan-Kettering Institute for Cancer Research in New York City, he was Assistant Professor and Firmenich As more