Synthesis

Companies Synthesis

MLS GmbH, Germany

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Chemspeed Technologies AG, Switzerland

Chemspeed is a global leader in the development of innovative instruments and consumables for scientists working in research and development laboratories including a line of fully automated parallel synthesizers, instruments for high throughput solid dispensing and liquid handling, and workstations more

CEM GmbH, Germany

CEM is the leading provider of microwave solutions for the laboratory, industrial and scientific marketplace. Since creating this market 20 years ago, we have sold almost 20,000 systems. Despite this obvious success, we believe microwave chemistry is still an emerging technology and presents tremend more

Products Synthesis

Microwave Peptide Synthesis – Pure Peptides in a Few Hours

Microwave energy offers benefits for both the coupling and deprotection reactions during peptide synthesis more

Where Are Your Limits? With Berghof High-Pressure Reactors More Flexibility in Synthesis

The modular design and flexible configuration options of Berghof highpreactor are a convincing response to the requirements of modern synthesis laboratories more

Look up Industrial Syntheses of 2,600 APIs

One-stop source of information relating to the industrial synthesis and commercial applications of every licensed drug of significance more

News Synthesis

• New synthesis approach for soluble silicon clusters
  

  Theoretical calculations indicate that under certain conditions silicon can endow solar cells with a much higher efficiency. Small silicon clusters may provide a source of accordingly modified silicon. However, to date these clusters have not been accessible in soluble form, a prerequisite for flexi more

• Sponge-like 2D material with interesting electrical conductivity and magnetic properties
  

  Chemists at the Center for Multidimensional Carbon Materials (CMCM), within the Institute for Basic Science (IBS, South Korea), have reported the synthesis of a novel type of 2D metal organic framework (MOF) with interesting electrical conductivity and magnetic properties. Published in the Journal o more

• Evonik and Dow develop industrial-scale direct synthesis of propylene glycol from propylene and hydrogen peroxide
  

  Dow and Evonik have entered into an exclusive technology partnership. Together, they plan to bring a unique method for directly synthesizing propylene glycol (PG) from propylene and hydrogen peroxide to market maturity. The basis for the method, named HYPROSYN™, has been created over the last few ye more

Videos Synthesis

Where Are Your Limits? With Berghof High-Pressure Reactors More Flexibility in Synthesis

The modular design and flexible configuration options of Berghof highpreactor are a convincing response to the requirements of modern synthesis laboratories. Safety, reliability and economy are achieved through the use of high-quality materials combined with durable PTFE linings. Complete PTFE Linin more

Aspirin

In this video about aspirin we show you an old sample and make a new one. more

Improve Your Strategy for the Design of New Molecules

Science of Synthesis is your one-stop tool for full-text reviews of organic transformations and experimental procedures. The online reference work helps speed up your literature research and improve your strategy for the design of new molecules. Science of Synthesis provides a critical review of the more

White papers Synthesis

• Develop Syntheses More Efficiently: How to Save Time and Money by Laboratory Automation
  

  How to maximize the efficiency and quality of developing your synthesis through parallel method development using fully automated laboratory reactors more

• In Situ Monitoring of Chemical Reactions – A Molecular Video
  

  While the technique has gained increased popularity in recent times, the principal of in situ reaction monitoring dates back to 1961 when Farenfort introduced a new method of measurement that today is called Attenuated Total Reflectance (ATR). The co more

• Pfizer Evaluates New Automated Sampling Technique
  

  This paper reviews the advantages of automated sampling, and four case studies testing the practice of EasySampler at Pfizer for impurity profiling more

Job offers Synthesis

• Research Scientist (m/f/d)
  

  The Global Competence Center Specialty Polymers within Group Technology & Innovation is looking for a creative and motivated Research Scientist (m/f/d) to execute its R&D projects, advancing laboratory practice and lead & develop its coworkers. Clariant is a focused and innovative specialty chemical more

Publications Synthesis

• Silver(I)-catalyzed sequential hydroamination and Prins type cyclization for the synthesis of fused benzo--sultams

  An intramolecular annulation strategy has been developed for the synthesis of tetrahydrobenzo[e]pyrano[4,3-c][1,2]thiazine derivatives by means of coupling of aldehydes with 2-(4-hydroxybut-1-yn-1-yl)-N-arylsulfonamides using a catalytic amount of silver hexafluoroantimonate in toluene at 80 °C. Thi more

• An efficient iodine pentoxide-triggered iodocarbocyclizations for the synthesis of iodooxindoles in water

  An efficient iodocarbocyclization of alkenes for the synthesis of iodooxindoles has been developed. This reaction proceeds in a chemoselective manner and shows excellent tolerance of various functional groups, including a chemosensitive hydroxymethyl group. Nonmetal inorganic iodine pentoxide was us more

• Copper-Catalyzed Cyclization of 2-Cyanobenzaldehydes and 2-Isocyanoacetates: an Efficient Strategy for the Synthesis of Substituted 1-Aminoisoquinolines

  A Cu(acac)2-catalyzed cyclization reaction of 2-cyanobenzaldehydes with 2-isocyanoacetates has been successfully developed providing an efficient strategy for the synthesis of substituted 1-aminoisoquinoline. The reaction proceeds smoothly under mild conditions with high efficiency, and might provid more

q&more articles Synthesis

• Modular biofactories at the cellular level
  

  Despite his love for complex molecular architectures, this „dyed-in-the-wool“ bio-organic chemist has never embraced the conventional segregation of synthetic polymers and bio­logical macromolecules. All molecules are composed of atoms, after all. Why make an artificial distinction? Why not simply combine these domains together? more

• The Beginning of the End?
  

  Those of us who have been either directly involved in, or on the periphery of, the pharmaceutical industry over the last decade have seen at first hand a dramatic change. Times change, and technology changes. Take computer data storage for example. Not so long ago, the floppy disk was state of the art, replaced by the CD-ROM, and then by the USB drive. more

• With Light in the Fight against Malaria
  

  Malaria represents a global threat to health, which is difficult to keep under control. Amongst more than 200 million sufferers, over 500,000 die each year of the disease, with the risk of a fatal outcome being particularly high in children [1]. more

Authors Synthesis

• Mathies V. Evers
  

  Mathies Evers, born in 1989, studied chemistry at the Ruhr University Bochum, where he researched the synthesis of atom-precise molecular clusters. After his master's degree he started his doctoral thesis at the Chair of Analytical Chemistry II of Professor Dr. Kristina Tschulik and is supported by more

• Prof. Dr. Peter Seeberger
  

  born 1966, studied chemistry at the University of Erlangen-Nuremberg, and received his doctorate in biochemistry from the University of Colorado. After holding a post-doctorate position at the Sloan-Kettering Institute for Cancer Research in New York City, he was Assistant Professor and Firmenich As more