Synthesis

Companies Synthesis

MLS GmbH, Germany

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CEM GmbH, Germany

CEM is the leading provider of microwave solutions for the laboratory, industrial and scientific marketplace. Since creating this market 20 years ago, we have sold almost 20,000 systems. Despite this obvious success, we believe microwave chemistry is still an emerging technology and presents tremend more

Chemspeed Technologies AG, Switzerland

Chemspeed is a global leader in the development of innovative instruments and consumables for scientists working in research and development laboratories including a line of fully automated parallel synthesizers, instruments for high throughput solid dispensing and liquid handling, and workstations more

Products Synthesis

Look up Industrial Syntheses of 2,600 APIs

One-stop source of information relating to the industrial synthesis and commercial applications of every licensed drug of significance more

Microwave Peptide Synthesis – Pure Peptides in a Few Hours

Microwave energy offers benefits for both the coupling and deprotection reactions during peptide synthesis more

Preparative HPLC: Flexibility Meets Convenience

The unique Azura prep HPLC systems: Multifunctional preparative HPLC systems you can easily adapt to specific sample purification challenges more

News Synthesis

• Development of an Efficient Enantioselective Desymmetrization Strategy Using Recombinant Pig Liver Esterases
  

  An economically significant process intensification for the efficient enzymatic synthesis of (1S,2R)-1-(methoxycarbonyl) cyclohex-4-ene-2-carboxylic acid was achieved by a careful adaption of the reaction mode to minimize mass transfer limitations. (1S,2R)-1-(methoxycarbonyl) cyclohex-4-ene-2-carbox more

• Energy-saving new LED phosphor
  

  The human eye is particularly sensitive to green, but less sensitive to blue and red. Chemists led by Hubert Huppertz at the University of Innsbruck have now developed a new red phosphor whose light is well perceived by the eye. This increases the light yield of white LEDs by around one sixth, which more

• Neutral Zinc-air battery with cathode NiCo/C-N shows outstanding performance
  

  A team of researchers from the School of Chemistry and Chemical Engineering at Hunan University of Science and Technology have proposed a novel strategy for the synthesis of non-precious metal catalysts in zinc-air batteries that do not compromise its electroactivity, affordability and stability. As more

Videos Synthesis

Aspirin

In this video about aspirin we show you an old sample and make a new one. more

Where Are Your Limits? With Berghof High-Pressure Reactors More Flexibility in Synthesis

The modular design and flexible configuration options of Berghof highpreactor are a convincing response to the requirements of modern synthesis laboratories. Safety, reliability and economy are achieved through the use of high-quality materials combined with durable PTFE linings. Complete PTFE Linin more

Improve Your Strategy for the Design of New Molecules

Science of Synthesis is your one-stop tool for full-text reviews of organic transformations and experimental procedures. The online reference work helps speed up your literature research and improve your strategy for the design of new molecules. Science of Synthesis provides a critical review of the more

White papers Synthesis

• Innovative Techniques to Synthesize Breakthrough Molecules
  

  Four case studies highlight how top pharmaceutical companies are implementing new synthesis techniques and the impact on the chemical synthesis lab more

• Chemists Need Tools that Allow them to Better Profile Organo-Metallic Reactions
  

  Advantages of automated sampling in a case study testing the practice of EasySampler for reaction profiling of an organo-metallic reaction more

• "Green Chemstry" in the Laboratory
  

  The term "green chemistry" is commonly used to describe chemical procedures which meet specific requirements with regards to the conservation of resources and protection of the environment. The objective is to avoid undesired by-products by selecting more

Events Synthesis

Job offers Synthesis

• Chemist / Chemical Engineer (m/f/d)
  

  To support our department „Zeolites“ in the R&D Center Heufeld of the Business Unit Catalysts we look for an experienced scientist with extended experience in the area of synthesis, modification and application of zeolite based catalysts. Clariant is a focused and innovative specialty chemical compa more

Publications Synthesis

• Silver(I)-catalyzed sequential hydroamination and Prins type cyclization for the synthesis of fused benzo--sultams

  An intramolecular annulation strategy has been developed for the synthesis of tetrahydrobenzo[e]pyrano[4,3-c][1,2]thiazine derivatives by means of coupling of aldehydes with 2-(4-hydroxybut-1-yn-1-yl)-N-arylsulfonamides using a catalytic amount of silver hexafluoroantimonate in toluene at 80 °C. Thi more

• An efficient iodine pentoxide-triggered iodocarbocyclizations for the synthesis of iodooxindoles in water

  An efficient iodocarbocyclization of alkenes for the synthesis of iodooxindoles has been developed. This reaction proceeds in a chemoselective manner and shows excellent tolerance of various functional groups, including a chemosensitive hydroxymethyl group. Nonmetal inorganic iodine pentoxide was us more

• Copper-Catalyzed Cyclization of 2-Cyanobenzaldehydes and 2-Isocyanoacetates: an Efficient Strategy for the Synthesis of Substituted 1-Aminoisoquinolines

  A Cu(acac)2-catalyzed cyclization reaction of 2-cyanobenzaldehydes with 2-isocyanoacetates has been successfully developed providing an efficient strategy for the synthesis of substituted 1-aminoisoquinoline. The reaction proceeds smoothly under mild conditions with high efficiency, and might provid more

q&more articles Synthesis

• With Light in the Fight against Malaria
  

  Malaria represents a global threat to health, which is difficult to keep under control. Amongst more than 200 million sufferers, over 500,000 die each year of the disease, with the risk of a fatal outcome being particularly high in children [1]. more

• Modular biofactories at the cellular level
  

  Despite his love for complex molecular architectures, this „dyed-in-the-wool“ bio-organic chemist has never embraced the conventional segregation of synthetic polymers and bio­logical macromolecules. All molecules are composed of atoms, after all. Why make an artificial distinction? Why not simply combine these domains together? more

• The Beginning of the End?
  

  Those of us who have been either directly involved in, or on the periphery of, the pharmaceutical industry over the last decade have seen at first hand a dramatic change. Times change, and technology changes. Take computer data storage for example. Not so long ago, the floppy disk was state of the art, replaced by the CD-ROM, and then by the USB drive. more

Authors Synthesis

• Prof. Dr. Peter Seeberger
  

  born 1966, studied chemistry at the University of Erlangen-Nuremberg, and received his doctorate in biochemistry from the University of Colorado. After holding a post-doctorate position at the Sloan-Kettering Institute for Cancer Research in New York City, he was Assistant Professor and Firmenich As more