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CEM is the leading provider of microwave solutions for the laboratory, industrial and scientific marketplace. Since creating this market 20 years ago, we have sold almost 20,000 systems. Despite this obvious success, we believe microwave chemistry is still an emerging technology and presents tremend more
Chemspeed is a global leader in the development of innovative instruments and consumables for scientists working in research and development laboratories including a line of fully automated parallel synthesizers, instruments for high throughput solid dispensing and liquid handling, and workstations more
Real-time measurement in less than a second, independent of turbidity, colour, absorption, viscosity ✓ Process temperatures up to 150°C and ATEX certification ✓ Nearly unlimited mounting flexibility due to compact design and various adaptors more
Built according to your specifications using highly corrosion resistant materials. ✓ Modular setup for customized configuration and easy upgradability. ✓ Smart design features allows for safe & effortless handling and operation. ✓ more
Microwave high pressure system ✓ Quick heating up ✓ Synthesis at up to 190 bar and 300 °C ✓ Permanent pressure and temperature control ✓ more
Long-term stability for battery materials through precise, even coating of anode/cathode materials Unique new optical effects and maximum protection for your paint and coating pigments more
Acetals are important chemical compounds that are used, for example, in the production of certain medical agents. A new method now makes their synthesis easier and more environmentally friendly. Chemists at the University of Bonn have developed and optimized the sustainable catalytic process. State- more
Whether in beta-blockers to treat high blood pressure or in natural products: So-called vicinal aminoalcohols are high-quality organic compounds that are found in many everyday products. However, their production is difficult. For a long time, chemists are trying to develop efficient methods of synt more
Chemists at the University of Bonn have synthesized extremely unusual compounds. Their central building block is a silicon atom. Different from usual, however, is the arrangement of the four bonding partners of the atom, which are not in the form of a tetrahedron around it, but flat like a trapezoid more
CEM Corporation is transforming the way chemists perform peptide synthesis once again with the introduction of the Liberty Blue microwave peptide synthesizer. With 4 minute cycle times and a 90% solvent reduction, no other peptide synthesizer on the market can even come close to the performance of t more
From nano to micro: drying, coating and calcining in just one process step with synthesis reactors from Glatt. Produce and coat powder materials with new, previously unattained properties in the pulsating hot gas stream of the patented Glatt powder synthesis. Thanks to the particularly homogeneous t more
NR low-pressure reactors, DB metal-free reactors and DAB pressure vessels.Smart instrument concepts allow an easy handling of all Berghof reactors. Due to helpful tools, opening and closure of the reactors is fast and with few effort. Extensive accessories support an efficient use of the reactors.Ru more
Four case studies highlight how top pharmaceutical companies are implementing new synthesis techniques and the impact on the chemical synthesis lab more
While the technique has gained increased popularity in recent times, the principal of in situ reaction monitoring dates back to 1961 when Farenfort introduced a new method of measurement that today is called Attenuated Total Reflectance (ATR). The co more
How to maximize the efficiency and quality of developing your synthesis through parallel method development using fully automated laboratory reactors more
An intramolecular annulation strategy has been developed for the synthesis of tetrahydrobenzo[e]pyrano[4,3-c][1,2]thiazine derivatives by means of coupling of aldehydes with 2-(4-hydroxybut-1-yn-1-yl)-N-arylsulfonamides using a catalytic amount of silver hexafluoroantimonate in toluene at 80 °C. Thi more
An efficient iodocarbocyclization of alkenes for the synthesis of iodooxindoles has been developed. This reaction proceeds in a chemoselective manner and shows excellent tolerance of various functional groups, including a chemosensitive hydroxymethyl group. Nonmetal inorganic iodine pentoxide was us more
A Cu(acac)2-catalyzed cyclization reaction of 2-cyanobenzaldehydes with 2-isocyanoacetates has been successfully developed providing an efficient strategy for the synthesis of substituted 1-aminoisoquinoline. The reaction proceeds smoothly under mild conditions with high efficiency, and might provid more
Despite his love for complex molecular architectures, this „dyed-in-the-wool“ bio-organic chemist has never embraced the conventional segregation of synthetic polymers and biological macromolecules. All molecules are composed of atoms, after all. Why make an artificial distinction? Why not simply combine these domains together? more
For the first time, an efficient catalyst for palladium-catalyzed C–C bonding between aryl chlorides and alkyl lithium compounds has been found. This reaction enables simpler synthesis routes for important products, such as pharmaceuticals, while avoiding much salt waste. more
Those of us who have been either directly involved in, or on the periphery of, the pharmaceutical industry over the last decade have seen at first hand a dramatic change. Times change, and technology changes. Take computer data storage for example. Not so long ago, the floppy disk was state of the art, replaced by the CD-ROM, and then by the USB drive. more
Mathies Evers, born in 1989, studied chemistry at the Ruhr University Bochum, where he researched the synthesis of atom-precise molecular clusters. After his master's degree he started his doctoral thesis at the Chair of Analytical Chemistry II of Professor Dr. Kristina Tschulik and is supported by more
Burkhard König, born in 1963, received his Ph.D. in 1991 from the University of Hamburg. He continued his scientific education as a post-doctoral fellow with Prof. M. A. Bennett, Research School of Chemistry, Australian National University, Canberra, and Prof. B. M. Trost, Stanford University. Since more
born 1966, studied chemistry at the University of Erlangen-Nuremberg, and received his doctorate in biochemistry from the University of Colorado. After holding a post-doctorate position at the Sloan-Kettering Institute for Cancer Research in New York City, he was Assistant Professor and Firmenich As more
Asymmetric synthesis Asymmetric synthesis, also called chiral synthesis, enantioselective synthesis or stereoselective synthesis, is organic synthesis which introduces one or more new and desired elements of chirality . This is important in th ... more
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