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Discovery and name
Mandelic acid was discovered while heating an extract of bitter almonds with diluted hydrochloric acid. The name is derived from the German "Mandel" for "almond".
It is an isomer of cresotinic acid (2-hydroxy-3-methylbenzoic acid) and oxymethylbenzoic acid (2-methoxybenzoic acid). Derivatives of mandelic acid are formed as a result of metabolism of adrenaline and noradrenaline by monoamine oxidase and catechol-o-methyl transferase. It is also present in certain skin care products, is an intermediate molecule in the production of other biochemicals, may be used as an analytical reagent and is a precursor in the manufacture of dyes.
It may be prepared by the action of hydrochloric acid on the addition compound of benzaldehyde and hydrocyanic acid, by boiling phenylchloracetic acid with alkalis, by heating benzoyl formaldehyde with alkalis or by the action of dilute alkalis on ω-dibromacetophenone.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Mandelic_acid". A list of authors is available in Wikipedia.|