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Acatalasia




Acatalasia
Classification & external resources
Basic structure of a peroxisome
ICD-10 E80.3
OMIM 115500
DiseasesDB 30598
MeSH D020642

Acatalasia (also called acatalasemia, or Takahara's disease) is an autosomal recessive peroxisomal disorder caused by a complete lack of catalase.

The disorder is relatively benign, although it causes an increased incidence of periodontal infections, and can under rare circumstances lead to gangrene.[citation needed]

History

In 1948 , Dr.Shigeo Takahara (1908-1994), a Japanese otolaryngologist first reported this new disease.[citation needed] He had examined a patient with an oral ulcer. He had spread hydrogen peroxide on the diseased part, but oxygen was not generated due to the lack of catalase.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Acatalasia". A list of authors is available in Wikipedia.
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