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Rotor syndrome



Rotor syndrome
Classification & external resources
Bilirubin
ICD-10 E80.6
ICD-9 277.4
OMIM 237450
DiseasesDB 11671
MeSH D006933

Rotor syndrome is a rare, relatively benign autosomal recessive bilirubin disorder of unknown origin.

Additional recommended knowledge

Contents

Presentation

It has many things in common with Dubin-Johnson syndrome except that in Rotor Syndrome, the liver cells are not pigmented. The main symptom is a non-itching jaundice. There is a rise in bilirubin in the patient's serum, mainly of the conjugated type.

It can be differentiated from Dubin-Johnson syndrome in the following ways:

Rotor syndrome DJS
appearance of liver normal histology and appearance liver has black pigmentation
gallbladder visualization gallbladder can be visualized by USG gallbladder cannot be visualized
total urine coproporphyrin content high with <70% being isomer 1 normal with >80% being isomer 1 (normal urine contains more of isomer 3 than isomer 1)

Eponym

Rotor syndrome is named after the Filipino internist, Arturo Belleza Rotor (1907-1988).[1]

See also

References

  1. ^ synd/2296 at Who Named It


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Rotor_syndrome". A list of authors is available in Wikipedia.
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