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Systematic (IUPAC) name
1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS number 153-61-7
ATC code J01DB03
PubChem 6024
DrugBank APRD00859
Chemical data
Formula C16H16N2O6S2 
Mol. mass 396.44 g/mol
Pharmacokinetic data
Bioavailability n/a
Protein binding 65 to 80%
Metabolism Hepatic
Half life 30 minutes to 1 hour
Excretion Renal
Therapeutic considerations
Pregnancy cat.


Legal status

Prescription Only (S4)(AU) POM(UK)

Routes IV

Cefalotin (INN) (pronounced /sɛfəˈlotən/, /kɛfə-/) or cephalothin (USAN) (/sɛfəˈloθən/, /kɛfə-/) is a first-generation cephalosporin antibiotic. It was the first cephalosporin marketed and continues to be widely used. It is an intravenously-administered agent with a similar antimicrobial spectrum to cefazolin and the oral agent cefalexin. Cefalotin sodium is commonly marketed under the trade name Keflin (Lilly).

See also

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cefalotin". A list of authors is available in Wikipedia.
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