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Cefprozil



Cefprozil
Systematic (IUPAC) name
8-[2-amino-2-(4-hydroxyphenyl)-acetyl] amino-7-oxo-4-prop-1-enyl-2-thia-6- azabicyclo [ 4.2.0]oct-4-ene-5-carboxylic acid
Identifiers
CAS number 92665-29-7
ATC code J01DC10
PubChem 5281006
DrugBank APRD00461
Chemical data
Formula C18H19N3O5S 
Mol. mass 389.427 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 36%
Metabolism  ?
Half life 1.3 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Cefprozil, sometimes spelled cefproxil and sold under the brand name Cefzil, is a cephalosporin type antibiotic. In Europe, it is sold by the name Procef. It can be used to treat bronchitis, ear infections, skin infections, and other bacterial infections. It comes as a tablet and as a liquid suspension.

Although there is a widely quoted cross-allergy risk of 10% between cephalosporins and penicillin, an article in the Journal of Family Practice (February 2006)[1] has shown no increased risk for cross-allergy for cefprozil and several other 2nd generation or later cephalosporins.

References

  1. ^ http://www.jfponline.com/pdf%2F5502%2F5502JFP_AppliedEvidence1.pdf
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cefprozil". A list of authors is available in Wikipedia.
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