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Doripenem



Doripenem
Systematic (IUPAC) name
(4R,5S,6S)-6-(1-hydroxyethyl)-4-methyl-7-oxo-3-
[(3S,5S)-5-[(sulfamoylamino)methyl]pyrrolidin-3-yl]
sulfanyl-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Identifiers
CAS number 148016-81-3
ATC code  ?
PubChem 73303
Chemical data
Formula C15H24N4O6S2 
Mol. mass 420.50426 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism Renal
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes IM, IV

Doripenem is an ultra-broad spectrum injectable antibiotic. It is a beta-lactam and belongs to the subgroup of carbapenems. It was launched by Shionogi Co. of Japan under the brand name Finibax in 2005. It is particularly active against Pseudomonas aeruginosa.

Additional recommended knowledge

Doripenem was approved by the United States Food and Drug Administration on October 12, 2007, to be sold under the tradename Doribax.[1]

References

  1. ^ U.S. Food and Drug Administration (October 17 2007). "FDA Approves New Drug to Treat Complicated Urinary Tract and Intra-Abdominal Infections". Press release. Retrieved on 2007-10-25.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Doripenem". A list of authors is available in Wikipedia.
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