My watch list
my.chemeurope.com  
Login  

Cefradine



Cefradine
Systematic (IUPAC) name
(6R,7R)-7-{[(2R)-2-amino-2-(1-cyclohexa-1,4-
dienyl)acetyl]amino}-3-methyl-8-oxo-5-thia-
1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Identifiers
CAS number 38821-53-3
ATC code J01DB09
PubChem 38103
Chemical data
Formula C16H19N3O4S 
Mol. mass 349.406 g/mol
Pharmacokinetic data
Bioavailability Well absorbed
Protein binding <10%
Metabolism Nil
Half life 0.9 hours
Excretion Renal, unchanged
Therapeutic considerations
Pregnancy cat.

?

Legal status

Prescription only

Routes Oral, IM, IV

Cefradine (INN) or cephradine (former BAN) is a first generation cephalosporin antibiotic.

Additional recommended knowledge

Contents

Indications

It has similar spectrum of activity to cefalexin.

Dosage

Dosage by mouth for adults is 250–500 mg every 6 hours, or 500 mg to 1 g every 12 hours. In severe infections up to 1 g every 6 hours may be used. Dosages for children are based upon their weight with 25–50 mg/kg total daily dose given in 2–4 divided doses.

Formulations

Caspules containing 250 mg or 500 mg, Syrup containing 250 mg/5 ml, or vials for injection containing 500 mg or 1 g.

References

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cefradine". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE