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Formestane



Formestane
Systematic (IUPAC) name
(8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-
2,6,7,8,9,11,12,14,15,16-decahydro-1H-
cyclopenta[a]phenanthrene-3,17-dione
Identifiers
CAS number 566-48-3
ATC code L02BG02
PubChem 11273
Chemical data
Formula C19H26O3 
Mol. mass 302.408 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Formestane belongs to a class of drugs known as aromatase inhibitors. It is used in the treatment of estrogen-receptor positive breast cancer in post-menopausal women. It is available as an intramuscular depot injection (Lentaron).

Additional recommended knowledge

Formestane is often used to suppress estrogen production from anabolic steroids or prohormones.

Formestane has poor oral bioavailability and as such is no longer popular as many orally available aromatase inhibitors have been developed.

It is available as a supplement for bodybuilders in transdermal formulations.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Formestane". A list of authors is available in Wikipedia.
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