My watch list
my.chemeurope.com  
Login  

Lasofoxifene



Lasofoxifene
Systematic (IUPAC) name
(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
Identifiers
CAS number 180916-16-9
ATC code G3H
PubChem 216416
Chemical data
Formula C28H31NO2 
Mol. mass 413.55 or 563.64 (with tartrate)
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Lasofoxifene (INN) is a selective estrogen receptor modulator (SERM) which is under development for the prevention and treatment of osteoporosis and for the treatment of vaginal atrophy.

In September 2005, Pfizer Inc. received a non-approvable letter from the U.S. Food and Drug Administration regarding lasofoxifene (Oporia®), a selective estrogen receptor modulator for the prevention of osteoporosis.

Additional recommended knowledge

Contents

Mode of action

Chemistry

Adverse effects

References


     
    This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Lasofoxifene". A list of authors is available in Wikipedia.
    Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE