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Lasofoxifene



Lasofoxifene
Systematic (IUPAC) name
(5R,6S)-6-phenyl-5-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-5,6,7,8-tetrahydronaphthalen-2-ol
Identifiers
CAS number 180916-16-9
ATC code G3H
PubChem 216416
Chemical data
Formula C28H31NO2 
Mol. mass 413.55 or 563.64 (with tartrate)
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Lasofoxifene (INN) is a selective estrogen receptor modulator (SERM) which is under development for the prevention and treatment of osteoporosis and for the treatment of vaginal atrophy.

In September 2005, Pfizer Inc. received a non-approvable letter from the U.S. Food and Drug Administration regarding lasofoxifene (Oporia®), a selective estrogen receptor modulator for the prevention of osteoporosis.

Contents

Mode of action

Chemistry

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References


     
    This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Lasofoxifene". A list of authors is available in Wikipedia.
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