Agilent Technologies announces first step in creating a universal, performance-based LC/MS mass spectral library for easier data

21-May-2002

PALO ALTO, Calif., May 20, 2002 Agilent Technologies Inc. today announced a first step in creating universal, performance- based searchable mass spectral libraries for liquid chromatography/mass spectrometry (LC/MS).

Such libraries are common for gas chromatography/mass spectrometry (GC/MS), enabling easier analytical data interpretation. However, because of differences in tune requirements, instrument parameters, and hardware, universal LC/MS libraries do not exist. LC/MS systems created on different systems have not been transferable.

Performance-based conditions, however, may offer an approach for making universal LC/MS libraries possible. The system is first tuned to fixed ion optic voltages and then set to the fragmentor voltage to meet the standardized ion-ratio criteria of the tune compounds. This enables performance-based results comparable from one instrument to another. A mass spectral library developed under performance-based conditions offers the possibility for use on any LC/MS system tuned to performance-based criteria.

For further information, request application note "Creating and Using a Performance-Based API-LC/ MSD Mass Spectral Library with NIST MS Search Software," Agilent publication number 5988-5445EN, which shows step-by-step procedures for tuning an LC/MS system to performance-based criteria, for creating a spectral library, and for searching the library. This note is available without charge from any Agilent sales office or Agilent's Web site at www.agilent.com/chem.

Other news from the department research and development

Most read news

More news from our other portals

Discover the latest developments in battery technology!

See the theme worlds for related content

Topic world Gas chromatography

Gas chromatography is an essential method in analytical chemistry for the separation and analysis of volatile compounds. Due to its high resolution and sensitivity, it has become firmly established in areas such as environmental analysis, food chemistry or forensic science. GC provides precise and reliable results and enables deep insights into the chemical composition of samples.

10+ products
2 whitepaper
10+ brochures
View topic world

Topic world Gas chromatography

Gas chromatography is an essential method in analytical chemistry for the separation and analysis of volatile compounds. Due to its high resolution and sensitivity, it has become firmly established in areas such as environmental analysis, food chemistry or forensic science. GC provides precise and reliable results and enables deep insights into the chemical composition of samples.

10+ products
2 whitepaper
10+ brochures

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

50+ products
20+ whitepaper
40+ brochures
View topic world

Topic World Chromatography

Chromatography enables us to separate, identify and thus understand complex substances. Whether in the food industry, pharmaceutical research or environmental analysis - chromatography opens up a treasure trove of information about the composition and quality of our samples. Discover the fascinating world of chromatography!

50+ products
20+ whitepaper
40+ brochures

Topic World Mass Spectrometry

Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!

15+ products
5 whitepaper
10+ brochures
View topic world

Topic World Mass Spectrometry

Mass spectrometry enables us to detect and identify molecules and reveal their structure. Whether in chemistry, biochemistry or forensics - mass spectrometry opens up unexpected insights into the composition of our world. Immerse yourself in the fascinating world of mass spectrometry!

15+ products
5 whitepaper
10+ brochures