14-Aug-2013 - Università Ca' Foscari

Increasing substrate selectivity through encapsulation

Italian chemists have come up with a homogenous catalytic system that displays substrate selectivity by developing an encapsulated catalyst that mimics enzymes to selectively hydrate one alkyne over a mixture of others.

The scientists encapsulated an NHC-Au(I) catalyst within a supramolecular host that acts like an enzyme so that only specific substrates will fit into the residual cavity left by the catalyst. Supramolecular interactions between the substrate, host and catalyst provide an additional level of electronic restrictions. They investigated the effect of the new catalyst on substrate selectivity in the hydration of alkenes that differed only remotely with respect to the active triple bond and found that, although the reactions were sluggish, the catalyst was significantly selective due to increased catalyst-substrate surface interactions.

Facts, background information, dossiers
  • Università Ca' Foscari
More about Università Ca' Foscari
  • News

    Nanomaterials: What are the environmental and health risks?

    From nanoscale silver to titanium dioxide for air purification, the use of nanomaterials of high commercial relevance proves to have clear benefits as it attracts investments, and raises concerns. 'Nano' sized materials (a nanometre is one millionth of a millimetre) could pose environmental ... more

More about Royal Society of Chemistry
  • News

    New coating is self-defence for seeds

    Scientists in Switzerland have developed a protective coating for seeds that poisons pests with cyanide when they bite into it. The coating is a system of two layers and only becomes toxic when the layers are mixed, eliminating the problem of environmental contamination that is associated w ... more

    Using bacteria to make electrodes

    Scientists in France have produced hematite using a bacterial pathway for use as an electrode material in Li-ion technologies. Currently, most commercial electrode materials for Li-ion technologies are prepared using the ceramic method, which requires long heating periods at high temperatur ... more

    Marine plant replacement for platinum in solar cells

    An international research team has shown that that the power conversion efficiency of sea tangle extract is comparable to platinum in solar cell electrodes. Dye-sensitized solar cells (DSCs) are quickly becoming a widespread and affordable alternative to photovoltaic solar cells. The electr ... more

  • Videos

    Royal Society of Chemistry – About us

    With more than 51,000 members and an international publishing and knowledge business we are the UK’s professional body for chemical scientists, supporting and representing our members and bringing together chemical scientists from all over the world. more

    A career in toxicology

    Hear from RSC member Vicki Stone talk about her role as a Nanotoxicologist. more

    When Food met Pharma: Delivery Strategies for Nutraceuticals

    With growing prevalence of lifestyle-associated diseases, including obesity, Type II diabetes and cardiovascular disease, there is an urgent need and demand to try to prevent the onset of these diseases within our growing population. Nutraceuticals, along with appropriate diet and exercise, ... more

  • Companies

    Royal Society of Chemistry (RSC)

    The RSC is a leading international publisher of highly regarded journals and books in the chemical sciences. The RSC is also the professional body for chemists with a global membership of over 46,000. more