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Monoamine neurotransmitter



Monoamine neurotransmitters are neurotransmitters and neuromodulators that contain one amino group that is connected to an aromatic ring by a two-carbon chain (-CH2-CH2-). All monoamines are derived from aromatic amino acids like phenylalanine, tyrosine, tryptophan, and the thyroid hormones by the action of aromatic amino acid decarboxylase enzymes.

Additional recommended knowledge

Examples

Specific transporter proteins called monoamine transporters exist that transport monoamines in or out of a cell. These are the dopamine transporter (DAT), serotonin transporter (SERT), and the norepinephrine transporter (NET) in the outer cell membrane and the vesicular monoamine transporter (VMAT1 and VMAT2) in the membrane of intracellular vesicles.

Monoamine oxidase is an enzyme that breaks down monoamine neurotransmitters after they have been released into the synapse.

See also

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Monoamine_neurotransmitter". A list of authors is available in Wikipedia.
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