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Naringin



Naringin
Systematic name 7-[[2-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-
glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-
2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Other names Naringin
4',5,7-Trihydroxyflavanone-7-rhamnoglucoside
4',5,7-Trihydroxyflavanone-7-rutinoside
Chemical formula C27H32O14
Molecular mass 580.541 g/mol
Density  ? g/cm3
Melting point 166 °C
CAS number [10236-47-2]
SMILES OC(C=C3)=CC=[C@@]3[C@@H]2CC(C1=C(O)
C=C(O[C@H]4[C@H](O[C@]5([H])O[C@@H]
(C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)
[C@H](O)[C@@H](CO)O4)C=C1O2)=O
Disclaimer and references

Naringin is the major flavonoid glycoside in grapefruit and gives grapefruit juice its bitter taste. It is metabolized to the flavanone naringenin in humans. Both naringenin and hesperetin, which are the aglycones of naringin and hesperidin, occur naturally in citrus fruits.

Additional recommended knowledge

Activity

Narinigin exerts a variety of pharmacological effects such as antioxidant activity, blood lipid-lowering, anticarcinogenic activity, and inhibition of selected cytochrome P450 enzymes including CYP3A4 and CYP1A2, which may result in several drug interactions in-vitro. [1]

References

  1. ^ Grapefruit Juice and Medications
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Naringin". A list of authors is available in Wikipedia.
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