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Valrubicin



Valrubicin
Systematic (IUPAC) name
[2-oxo-2-[2,5,12-trihydroxy-4- [5-hydroxy-6-methyl-4- (2,2,2-trifluoroacetyl) amino-tetrahydropyran-2-yl] oxy-7-methoxy-6,11-dioxo-1,2,3,4-tetrahydrotetracen- 2-yl]-ethyl] pentanoate
Identifiers
CAS number 56124-62-0
ATC code L01DB09
PubChem 41744
DrugBank APRD00662
Chemical data
Formula C34H36F3NO13 
Mol. mass 723.644 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding >99%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Valrubicin (N-trifluoroacetyladriamycin-14-valerate, Valstar®) is a chemotherapy drug used to treat bladder cancer. Valrubicin is a semisynthetic analog of the anthracycline doxorubicin, and is administered by infusion directly into the bladder.

Additional recommended knowledge

Dosage

800 mg weekly for 6 weeks

Side effects

  • Blood in urine
  • Incontinence
  • painful or difficult urination
  • Unusually frequent urination


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Valrubicin". A list of authors is available in Wikipedia.
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